Table 4.

The PLASMIC score to predict TTP associated with severe ADAMTS13 deficiency

InvestigationPoint
Platelet count < 30 × 109/L 
Hemolysis variable* 
No active cancer 
No history of HSCT 
MCV < 90 fL 
INR < 1.5 
Creatinine < 2.0 mg/dL 
InvestigationPoint
Platelet count < 30 × 109/L 
Hemolysis variable* 
No active cancer 
No history of HSCT 
MCV < 90 fL 
INR < 1.5 
Creatinine < 2.0 mg/dL 

INR, international normalized ratio; MCV, mean cell volume. Reprinted from Bendapudi et al48  with permission.

*

Reticulocyte count >2.5% or undetectable haptoglobin or indirect bilirubin >2.0 mg/dL.

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