Table 1.

Risk of CNS relapse in DLBCL treated with R-CHOP(-like) chemotherapy using the CNS-IPI

Study cohortNumber of patients2-y risk of CNS relapse
Overall (all DLBCL)Low (0-1 factors)Intermediate (2-3 factors)High (4-5 factors)
DSHNHL (7) 2164* 4% 0.6% 3.4% 10.2% 
BCCA (7) 1597 4% 0.8% 3.9% 12% 
Danish (9) 1532 4% (3 y) 0.4% (3 y) 3% (3 y) 11% (3 y) 
Study cohortNumber of patients2-y risk of CNS relapse
Overall (all DLBCL)Low (0-1 factors)Intermediate (2-3 factors)High (4-5 factors)
DSHNHL (7) 2164* 4% 0.6% 3.4% 10.2% 
BCCA (7) 1597 4% 0.8% 3.9% 12% 
Danish (9) 1532 4% (3 y) 0.4% (3 y) 3% (3 y) 11% (3 y) 

*DLBCL n = 1735 (80%); sensitivity analysis produced similar results.

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