Table 3.

Efficacy and safety data for lead JAK inhibitors in patients with MF

Efficacy and safety data for lead JAK inhibitors in patients with MF
Efficacy and safety data for lead JAK inhibitors in patients with MF

PPV/PET MF indicates post-polycythemic/post-ET MF; RUX, ruxolitinib; PBO, placebo; TSS, total symptom score; IWG-MRT, International Working Group for Myeloproliferative Neoplasms Research and Treatment; AE, adverse event; DLT, dose-limiting toxicity; ALT, alanine aminotransferase; AST, aspartate amino transferase; MTD, maximum tolerated dose; EORTC, European Organization for Research and Treatment of Cancer; and Fact-Lym, Functional Assessment of Cancer Therapy-Lymphoma.

*Several studies use different measurements for symptoms and therefore it is not possible to compare symptomatic improvements directly.

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