Table 1. CLL-IPI: final multivariable... | American Society of Hematology

Table 1.

CLL-IPI: final multivariable model

Characteristic	Adverse factor	Risk score	HR	95% CI	P
TP53 status	Deleted and/or mutated	4	4.2	3.2-5.5	<.001
IGHV mutational status	Unmutated	2	2.6	2.1-3.2	<.001
β₂-Microglobulin, mg/L	>3.5	2	2.0	1.6-2.4	<.001
Age, y	>65	1	1.7	1.4-2.1	<.001
Clinical stage	Rai IV or Binet B-C	1	1.6	1.3-1.9	<.001

Characteristic	Adverse factor	Risk score	HR	95% CI	P
TP53 status	Deleted and/or mutated	4	4.2	3.2-5.5	<.001
IGHV mutational status	Unmutated	2	2.6	2.1-3.2	<.001
β₂-Microglobulin, mg/L	>3.5	2	2.0	1.6-2.4	<.001
Age, y	>65	1	1.7	1.4-2.1	<.001
Clinical stage	Rai IV or Binet B-C	1	1.6	1.3-1.9	<.001

CI, confidence interval; HR, hazard ratio.