Prognostic and predictive biomarkers commonly used in clinical practice
.
Prognostic
.
Predictive
.
Age
CIRS
Stage
β2-microglobulin
CD49d
CD38
ZAP70
IGHV mutation
17p13 deletion
11q22-23 deletion
Trisomy 12
13q14 deletion
TP53 mutation
SF3B1 mutation
NOTCH1 mutation
.
Prognostic
.
Predictive
.
Age
CIRS
Stage
β2-microglobulin
CD49d
CD38
ZAP70
IGHV mutation
17p13 deletion
11q22-23 deletion
Trisomy 12
13q14 deletion
TP53 mutation
SF3B1 mutation
NOTCH1 mutation
A green circle indicates yes, a red circle indicates no, and an orange circle indicates not yet fully validated. CIRS, Cumulative Illness Rating Scale; IGHV, immunoglobulin heavy variable gene.