Table 1.

Prognostic and predictive biomarkers commonly used in clinical practice

PrognosticPredictive
Age   
CIRS   
Stage   
β2-microglobulin   
CD49d   
CD38   
ZAP70   
IGHV mutation   
17p13 deletion   
11q22-23 deletion   
Trisomy 12   
13q14 deletion   
TP53 mutation   
SF3B1 mutation   
NOTCH1 mutation   
PrognosticPredictive
Age   
CIRS   
Stage   
β2-microglobulin   
CD49d   
CD38   
ZAP70   
IGHV mutation   
17p13 deletion   
11q22-23 deletion   
Trisomy 12   
13q14 deletion   
TP53 mutation   
SF3B1 mutation   
NOTCH1 mutation   

A green circle indicates yes, a red circle indicates no, and an orange circle indicates not yet fully validated. CIRS, Cumulative Illness Rating Scale; IGHV, immunoglobulin heavy variable gene.

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