Population-attributable risk of inherited thrombophilia for VTE in pregnancy and the postpartum period
Inherited thrombophilia . | Proportion of attributable risk (%) . |
---|---|
All inherited thrombophilia | 48.3 |
FVL | |
Heterozygous | 26.7 |
Homozygous | 7.7 |
PGM | |
Heterozygous | 10.4 |
Homozygous | —* |
Compound FVL/PGM | —* |
PC deficiency | 1.9 |
PS deficiency | 1.5 |
AT deficiency | 0.07 |
No inherited thrombophilia | 51.7 |
Inherited thrombophilia . | Proportion of attributable risk (%) . |
---|---|
All inherited thrombophilia | 48.3 |
FVL | |
Heterozygous | 26.7 |
Homozygous | 7.7 |
PGM | |
Heterozygous | 10.4 |
Homozygous | —* |
Compound FVL/PGM | —* |
PC deficiency | 1.9 |
PS deficiency | 1.5 |
AT deficiency | 0.07 |
No inherited thrombophilia | 51.7 |
Population-attributable risk is calculated on the basis of relative risk of VTE in pregnancy16 and prevalence of thrombophilia in the general population.69
*Unknown estimates.