Table 1.

Pre- and posttest probability of HIT using a combined approach of the 4Ts and EIAs

ReferenceDesignNPretest probability of 4TsPosttest probability of 4Ts (+ assay/− assay)
Low (0-3)Intermediate (4-5)High (6-8)Low (0-3)Intermediate (4-5)High (6-8)
27 Single center, retrospective 1291 0.8% 14% 53% NR 65%/0% 95%/0% 
28 Multicenter, prospective 380 2.1% 11% 47% 11%/0.06% 42%/0.4% 83%/2.6% 
24 Multicenter, prospective 526 1.9% 7% 37% 15%/0% 42%/0% 88%/0% 
ReferenceDesignNPretest probability of 4TsPosttest probability of 4Ts (+ assay/− assay)
Low (0-3)Intermediate (4-5)High (6-8)Low (0-3)Intermediate (4-5)High (6-8)
27 Single center, retrospective 1291 0.8% 14% 53% NR 65%/0% 95%/0% 
28 Multicenter, prospective 380 2.1% 11% 47% 11%/0.06% 42%/0.4% 83%/2.6% 
24 Multicenter, prospective 526 1.9% 7% 37% 15%/0% 42%/0% 88%/0% 

EIA, enzyme immunoassay; NR, not reported.

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