Patient and transplant characteristics
Variables . | Median (range) or n (%) . |
---|---|
Age at HSCT, y | 14.5 (4-24) |
Sex | |
Female | 13 (36.1) |
Male | 23 (63.9) |
Lymphoma subtypes | |
ALCL | 14 (38.9) |
DLBCL | 8 (22.2) |
LL | 9 (25.0) |
Other lymphomas | 5 (13.9) |
Time to relapse after initial diagnosis, mo | |
≤12 | 12 (44.4) |
>12 | 15 (55.6) |
Disease status at HSCT | |
CR | 15 (42.9) |
PR | 17 (48.6) |
SD | 3 (8.6) |
Conditioning | |
MAC | 27 (75.0) |
RIC | 9 (25.0) |
TBI | |
TBI | 32 (88.9) |
Non-TBI | 4 (11.1) |
GVHD prophylaxis | |
CD34+ selection | 4 (11.1) |
CNI | 8 (22.2) |
CNI/MTX | 21 (58.3) |
Other | 3 (8.3) |
Cell source | |
Bone marrow | 26 (72.2) |
PBSCT | 10 (27.8) |
Donor type | |
MRD | 13 (36.1) |
MUD | 10 (27.8) |
MMUD | 9 (25.0) |
Haploidentical | 4 (11.1) |
Variables . | Median (range) or n (%) . |
---|---|
Age at HSCT, y | 14.5 (4-24) |
Sex | |
Female | 13 (36.1) |
Male | 23 (63.9) |
Lymphoma subtypes | |
ALCL | 14 (38.9) |
DLBCL | 8 (22.2) |
LL | 9 (25.0) |
Other lymphomas | 5 (13.9) |
Time to relapse after initial diagnosis, mo | |
≤12 | 12 (44.4) |
>12 | 15 (55.6) |
Disease status at HSCT | |
CR | 15 (42.9) |
PR | 17 (48.6) |
SD | 3 (8.6) |
Conditioning | |
MAC | 27 (75.0) |
RIC | 9 (25.0) |
TBI | |
TBI | 32 (88.9) |
Non-TBI | 4 (11.1) |
GVHD prophylaxis | |
CD34+ selection | 4 (11.1) |
CNI | 8 (22.2) |
CNI/MTX | 21 (58.3) |
Other | 3 (8.3) |
Cell source | |
Bone marrow | 26 (72.2) |
PBSCT | 10 (27.8) |
Donor type | |
MRD | 13 (36.1) |
MUD | 10 (27.8) |
MMUD | 9 (25.0) |
Haploidentical | 4 (11.1) |
CNI, calcineurin inhibitor; MAC, myeloablative conditioning; MMUD, mismatched unrelated donor; MRD, matched related donor; MTX, methotrexate; MUD, matched unrelated donor; PBSCT, peripheral blood stem cell transplant; RIC, reduced-intensity conditioning; TBI, total-body irradiation.