Table 1. Expected and obtained... | American Society of Hematology

Table 1.

Expected and obtained distribution of mice with various genotypes

Genotype	N	Expected, %	Observed, %
*a13^−/−cfh^W/W× a13^−/−cfh*^W/R
a13^−/−cfh^W/W	60	50	62.5*
a13^−/−cfh^W/R	36	50	37.5*
*a13^−/−cfh^W/R× a13^−/−cfh*^W/R
a13^−/−cfh^W/W	64	25	32.5
a13^−/−cfh^W/R	89	50	45.2
a13^−/−cfh^R/R	44	25	22.3

Genotype	N	Expected, %	Observed, %
*a13^−/−cfh^W/W× a13^−/−cfh*^W/R
a13^−/−cfh^W/W	60	50	62.5*
a13^−/−cfh^W/R	36	50	37.5*
*a13^−/−cfh^W/R× a13^−/−cfh*^W/R
a13^−/−cfh^W/W	64	25	32.5
a13^−/−cfh^W/R	89	50	45.2
a13^−/−cfh^R/R	44	25	22.3

A Student t test was performed for comparing the difference between the percent observed and expected. The null hypothesis value (percentage expected) is based on the Mendelian distribution.

a13^−/−, Adamts13 null; cfh, complement factor H; cfh^W/W, cfh^W/R, and cfh^R/R represent wild-type, heterozygous, and homozygous mutations in the gene encoding cfh at the position of 1206.

P < .05.

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