Demographics and comorbidities of patients with and without stroke
| Characteristic . | Total (N = 137) . | No stroke (n = 119) . | Stroke (n = 18) . | P* . |
|---|---|---|---|---|
| Age, median (IQR), y | 48.8 (35.3, 60.3) | 46.7 (34.9, 58.9) | 57.2 (49.9, 67.3) | .028 |
| Race, % | ||||
| White | 32.8 | 33.6 | 27.8 | .685 |
| African American | 62.0 | 60.5 | 72.2 | |
| Other | 5.0 | 5.8 | 0 | |
| Female sex, % | 67.9 | 65.5 | 83.3 | .178 |
| Stroke during acute TTP episode, % | 9.5 | 8.4 | 16.7 | .379 |
| Total number of TTP episodes, median, IQR | 1 (1, 2) | 1 (1, 2) | 2 (1, 2) | .083 |
| Hypertension, % | 45.3 | 41.2 | 72.2 | .021 |
| Diabetes mellitus, % | 22.6 | 20.2 | 38.9 | .126 |
| Obesity (BMI >30), % | 29.2 | 30.3 | 22.2 | .347 |
| Dyslipidemia, % | 17.5 | 15.1 | 33.3 | .090 |
| Atrial fibrillation, % | 5.8 | 5.9 | 5.6 | .956 |
| SLE, % | 8.0 | 6.7 | 16.7 | .160 |
| Other autoimmune disorder, % | 8.0 | 6.7 | 16.7 | .160 |
| Chronic kidney disease, % | 16.8 | 16.0 | 22.2 | .737 |
| Current smoking, % | 14.6 | 12.7 | 22.2 | .220 |
| Characteristic . | Total (N = 137) . | No stroke (n = 119) . | Stroke (n = 18) . | P* . |
|---|---|---|---|---|
| Age, median (IQR), y | 48.8 (35.3, 60.3) | 46.7 (34.9, 58.9) | 57.2 (49.9, 67.3) | .028 |
| Race, % | ||||
| White | 32.8 | 33.6 | 27.8 | .685 |
| African American | 62.0 | 60.5 | 72.2 | |
| Other | 5.0 | 5.8 | 0 | |
| Female sex, % | 67.9 | 65.5 | 83.3 | .178 |
| Stroke during acute TTP episode, % | 9.5 | 8.4 | 16.7 | .379 |
| Total number of TTP episodes, median, IQR | 1 (1, 2) | 1 (1, 2) | 2 (1, 2) | .083 |
| Hypertension, % | 45.3 | 41.2 | 72.2 | .021 |
| Diabetes mellitus, % | 22.6 | 20.2 | 38.9 | .126 |
| Obesity (BMI >30), % | 29.2 | 30.3 | 22.2 | .347 |
| Dyslipidemia, % | 17.5 | 15.1 | 33.3 | .090 |
| Atrial fibrillation, % | 5.8 | 5.9 | 5.6 | .956 |
| SLE, % | 8.0 | 6.7 | 16.7 | .160 |
| Other autoimmune disorder, % | 8.0 | 6.7 | 16.7 | .160 |
| Chronic kidney disease, % | 16.8 | 16.0 | 22.2 | .737 |
| Current smoking, % | 14.6 | 12.7 | 22.2 | .220 |
BMI, body mass index.
Fisher's exact test (categorical variables), Mann-Whitney U test (continuous variables).