Table 2.

Univariate changes in Hb levels after transfusion (N = 38 019)

VariableHb increment, g/dLP*
Overall change in Hb level 1.04 ± 0.89  
Blood donor characteristic   
 Donor sex  <.001 
  Male 1.08 ± 0.87  
  Female 1.01 ± 0.89  
 Donor age  .43 
  <20 y 1.05 ± 0.89  
  20-44 y 1.04 ± 0.89  
  45-70 y 1.05 ± 0.88  
  >70 y 1.02 ± 0.84  
 Donor Rh status  <.001 
  Negative 1.01 ± 0.89  
  Positive 1.06 ± 0.87  
 Donor ABO blood group†  .14 
  O 1.04 ± 0.90  
  Non-O 1.06 ± 0.89  
Blood component characteristic   
 Collection method  <.001 
  Apheresis-derived 0.97 ± 0.87  
  Whole blood 1.07 ± 0.88  
 Storage duration‡  .09 
  1-21 d 1.04 ± 0.89  
  22-28 d 1.05 ± 0.90  
  29-35 d 1.06 ± 0.86  
  36-42 d 1.05 ± 0.84  
 RBC solution, %  .80 
  AS-1 1.04 ± 0.89  
  AS-3 1.05 ± 0.87  
 Gamma irradiation  <.001 
  Yes 0.98 ± 0.81  
  No 1.06 ± 0.88  
Transfusion recipient characteristic   
 Recipient sex  <.0001 
  Male 0.91 ± 0.83  
  Female 1.19 ± 0.91  
 Recipient age  <.0001 
  18-55 y 0.96 ± 0.92  
  56-69 y 0.98 ± 0.87  
  70-80 y 1.05 ± 0.86  
  >80 y 1.16 ± 0.87  
 Recipient BMI  <.0001 
  Underweight 1.44 ± 0.96  
  Normal 1.16 ± 0.92  
  Overweight 1.03 ± 0.86  
  Obese 0.89 ± 0.80  
 Recipient Rh status  <.0001 
  Negative 1.00 ± 0.88  
  Positive 1.06 ± 0.88  
 Recipient ABO blood group†   
  O 1.04 ± 0.89  
  Non-O 1.05 ± 0.86  
 Pretransfusion Hb level  <.0001 
  <7 g/dL 1.26 ± 0.95  
  7-8 g/dL 1.11 ± 0.82  
  >8 g/dL 0.96 ± 0.89  
VariableHb increment, g/dLP*
Overall change in Hb level 1.04 ± 0.89  
Blood donor characteristic   
 Donor sex  <.001 
  Male 1.08 ± 0.87  
  Female 1.01 ± 0.89  
 Donor age  .43 
  <20 y 1.05 ± 0.89  
  20-44 y 1.04 ± 0.89  
  45-70 y 1.05 ± 0.88  
  >70 y 1.02 ± 0.84  
 Donor Rh status  <.001 
  Negative 1.01 ± 0.89  
  Positive 1.06 ± 0.87  
 Donor ABO blood group†  .14 
  O 1.04 ± 0.90  
  Non-O 1.06 ± 0.89  
Blood component characteristic   
 Collection method  <.001 
  Apheresis-derived 0.97 ± 0.87  
  Whole blood 1.07 ± 0.88  
 Storage duration‡  .09 
  1-21 d 1.04 ± 0.89  
  22-28 d 1.05 ± 0.90  
  29-35 d 1.06 ± 0.86  
  36-42 d 1.05 ± 0.84  
 RBC solution, %  .80 
  AS-1 1.04 ± 0.89  
  AS-3 1.05 ± 0.87  
 Gamma irradiation  <.001 
  Yes 0.98 ± 0.81  
  No 1.06 ± 0.88  
Transfusion recipient characteristic   
 Recipient sex  <.0001 
  Male 0.91 ± 0.83  
  Female 1.19 ± 0.91  
 Recipient age  <.0001 
  18-55 y 0.96 ± 0.92  
  56-69 y 0.98 ± 0.87  
  70-80 y 1.05 ± 0.86  
  >80 y 1.16 ± 0.87  
 Recipient BMI  <.0001 
  Underweight 1.44 ± 0.96  
  Normal 1.16 ± 0.92  
  Overweight 1.03 ± 0.86  
  Obese 0.89 ± 0.80  
 Recipient Rh status  <.0001 
  Negative 1.00 ± 0.88  
  Positive 1.06 ± 0.88  
 Recipient ABO blood group†   
  O 1.04 ± 0.89  
  Non-O 1.05 ± 0.86  
 Pretransfusion Hb level  <.0001 
  <7 g/dL 1.26 ± 0.95  
  7-8 g/dL 1.11 ± 0.82  
  >8 g/dL 0.96 ± 0.89  
*

P values correspond to Student t tests.

†

Non-O blood group includes A, B, and AB blood types.

‡

Increments for other storage solutions included in supplemental Table 3.

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