Table 1

Association constants of sERGIC-53 with MCFD2 at several CaCl2 concentrations and pH conditions

CaCl2, mMKa (M) at pH 6.0Ka (M) at pH 6.5Ka (M) at pH 7.0
0.05 1.05 × 106 1.54 × 106 2.18 × 106 
0.1 4.07 × 106 8.06 × 106 4.41 × 106 
0.2 3.95 × 107 4.46 × 107 3.92 × 107 
0.3 4.42 × 107 5.38 × 107 4.95 × 107 
0.5 8.33 × 107 7.94 × 107 8.00 × 107 
0.75 2.23 × 108 2.10 × 108 2.57 × 108 
1.0 1.67 × 108 3.56 × 108 1.69 × 108 
CaCl2, mMKa (M) at pH 6.0Ka (M) at pH 6.5Ka (M) at pH 7.0
0.05 1.05 × 106 1.54 × 106 2.18 × 106 
0.1 4.07 × 106 8.06 × 106 4.41 × 106 
0.2 3.95 × 107 4.46 × 107 3.92 × 107 
0.3 4.42 × 107 5.38 × 107 4.95 × 107 
0.5 8.33 × 107 7.94 × 107 8.00 × 107 
0.75 2.23 × 108 2.10 × 108 2.57 × 108 
1.0 1.67 × 108 3.56 × 108 1.69 × 108 
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