Table 6

Quality of life of hemophilia patients born before or after the introduction of prophylaxis

SevereModerate/mildGeneral population
Born before introduction of prophylaxis (30–65 y), no144 244 — 
    Physical functioning 45.9 (28.5) 83.1 (23.8) 84.0 (19.6) 
    Social functioning 72.5 (25.7) 83.5 (23.8) 83.5 (22.1) 
    Role-physical 49.5 (43.8) 78.4 (37.5) 74.5 (36.8) 
    Role-emotional 67.4 (42.9) 85.2 (33.0) 81.6 (33.2) 
    Mental health 73.4 (19.1) 76.6 (18.5) 75.6 (18.5) 
    Vitality 61.4 (20.7) 66.6 (21.1) 68.6 (20.2) 
    Bodily pain 64.5 (24.3) 82.5 (23.5) 71.8 (24.1) 
    General health perception 56.8 (23.5) 68.3 (23.3) 69.7 (20.6) 
Born after introduction of prophylaxis (15–30 y), no102 133 — 
    Physical functioning 82.2 (21.4) 94.0 (12.9) 93.1 (11.8) 
    Social functioning 87.6 (20.2) 91.4 (17.5) 87.8 (19.1) 
    Role-physical 73.0 (38.0) 90.4 (24.6) 86.4 (27.6) 
    Role-emotional 86.6 (29.0) 94.9 (20.3) 85.4 (30.0) 
    Mental health 79.9 (14.0) 80.1 (14.5) 78.7 (15.2) 
    Vitality 71.9 (15.1) 72.2 (15.6) 70.7 (16.4) 
    Bodily pain 76.9 (22.9) 88.7 (18.9) 80.9 (19.4) 
    General health 69.9 (22.2) 76.2 (18.3) 78.4 (17.3) 
SevereModerate/mildGeneral population
Born before introduction of prophylaxis (30–65 y), no144 244 — 
    Physical functioning 45.9 (28.5) 83.1 (23.8) 84.0 (19.6) 
    Social functioning 72.5 (25.7) 83.5 (23.8) 83.5 (22.1) 
    Role-physical 49.5 (43.8) 78.4 (37.5) 74.5 (36.8) 
    Role-emotional 67.4 (42.9) 85.2 (33.0) 81.6 (33.2) 
    Mental health 73.4 (19.1) 76.6 (18.5) 75.6 (18.5) 
    Vitality 61.4 (20.7) 66.6 (21.1) 68.6 (20.2) 
    Bodily pain 64.5 (24.3) 82.5 (23.5) 71.8 (24.1) 
    General health perception 56.8 (23.5) 68.3 (23.3) 69.7 (20.6) 
Born after introduction of prophylaxis (15–30 y), no102 133 — 
    Physical functioning 82.2 (21.4) 94.0 (12.9) 93.1 (11.8) 
    Social functioning 87.6 (20.2) 91.4 (17.5) 87.8 (19.1) 
    Role-physical 73.0 (38.0) 90.4 (24.6) 86.4 (27.6) 
    Role-emotional 86.6 (29.0) 94.9 (20.3) 85.4 (30.0) 
    Mental health 79.9 (14.0) 80.1 (14.5) 78.7 (15.2) 
    Vitality 71.9 (15.1) 72.2 (15.6) 70.7 (16.4) 
    Bodily pain 76.9 (22.9) 88.7 (18.9) 80.9 (19.4) 
    General health 69.9 (22.2) 76.2 (18.3) 78.4 (17.3) 

Data are means (SD).

— indicates exact number not known.

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