Table 3

Treatment-related toxicity

Arm A (n = 97)Arm B (n = 98)P
First autologous transplant    
    Patients, no. (%) 87 (90) 85 (87) NS 
    Median duration of neutropenia,* days (range) 8 (4–12) 8 (5–13) NS 
    Median duration of thrombocytopenia, days (range) 9 (2–19) 10 (2–20) NS 
    Platelet transfusions, no. (range) 4 (0–10) 3 (0–11) NS 
    Treatment-related deaths, no. NS 
Second autologous transplant    
    Patients, no. (%) 80 (82) 9 (9) NA 
    Median duration of neutropenia,* days (range) 9 (4–14) 10 (6–14) NS 
    Median duration of thrombocytopenia, days (range) 12 (4–22) 13 (6–23) NS 
    Platelet transfusions, no. (range) 5 (1–12) 5 (1–11) NS 
    Treatment-related deaths, no. NS 
Arm A (n = 97)Arm B (n = 98)P
First autologous transplant    
    Patients, no. (%) 87 (90) 85 (87) NS 
    Median duration of neutropenia,* days (range) 8 (4–12) 8 (5–13) NS 
    Median duration of thrombocytopenia, days (range) 9 (2–19) 10 (2–20) NS 
    Platelet transfusions, no. (range) 4 (0–10) 3 (0–11) NS 
    Treatment-related deaths, no. NS 
Second autologous transplant    
    Patients, no. (%) 80 (82) 9 (9) NA 
    Median duration of neutropenia,* days (range) 9 (4–14) 10 (6–14) NS 
    Median duration of thrombocytopenia, days (range) 12 (4–22) 13 (6–23) NS 
    Platelet transfusions, no. (range) 5 (1–12) 5 (1–11) NS 
    Treatment-related deaths, no. NS 

NS indicates not significant; and NA, not applicable.

*

Neutropenia: < 0.5 × 109 white cells/L.

Thrombocytopenia: < 50 × 109 platelets/L.

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