Characteristics of female 5-year survivors of allogeneic transplantation
| Characteristic . | All patients . | Patients with breast cancer . | Patients without breast cancer . |
|---|---|---|---|
| Patients, no. | 3337 | 52 | 3285 |
| Median age at transplantation, y (range) | 28.1 (0.2-70.3) | 32.9 (3.6-59.2) | 28.0 (0.2-70.3) |
| Median age at breast cancer, y (range) | N/A | 47.5 (25.5-65.8) | NA |
| Location of transplant center, no. (%) | |||
| EBMT | 2369 (71.0) | 29 (55.8) | 2340 (71.2) |
| FHCRC | 968 (29.1) | 23 (44.2) | 945 (28.8) |
| Age at HCT, no. (%) | |||
| Younger than 10 y | 549 (16.5) | 1 (1.9) | 548 (16.7) |
| 10 to 17 y | 477 (14.3) | 7 (13.5) | 470 (14.3) |
| 18 to 39 y | 1577 (47.2) | 25 (48.1) | 1552 (47.3) |
| 40 y or older | 734 (22.0) | 19 (36.5) | 715 (21.7) |
| Primary disease, no. (%) | |||
| Acute leukemia | 1364 (40.9) | 22 (42.3) | 1342 (40.9) |
| Chronic leukemia | 1060 (34.8) | 22 (42.3) | 1038 (31.6) |
| Myelodysplastic syndrome | 200 (6.0) | 1 (1.9) | 199 (6.1) |
| Multiple myeloma & plasma cell disorders | 52 (1.6) | 0 (0) | 52 (1.6) |
| Lymphoma | 94 (2.8) | 4 (7.7) | 90 (2.7) |
| Solid tumors | 7 (0.2) | 0 (0) | 7 (1.2) |
| Total body radiation (TBI), no. (%) | |||
| No | 1070 (32.1) | 5 (9.6) | 1065 (32.4) |
| Yes | 2162 (64.8) | 47 (90.4) | 2115 (64.4) |
| Unknown | 105 (3.1) | 0 | 105 (3.2) |
| Donor type, no. (%) | |||
| HLA-identical related | 2645 (79.3) | 43 (82.7) | 2602 (79.2) |
| HLA-mismatched related | 169 (5.0) | 3 (5.8) | 166 (5.0) |
| Unrelated | 494 (14.8) | 6 (11.5) | 488 (14.9) |
| Unknown | 29 (0.9) | 0 | 29 (0.9) |
| Acute graft-versus-host disease, no. (%) | |||
| None | 1142 (34.2) | 20 (38.5) | 1122 (34.2) |
| Grades 1 to 2 | 1723 (51.6) | 27 (51.9) | 1696 (51.6) |
| Grades 3 to 4 | 315 (9.4) | 5 (9.6) | 310 (9.4) |
| Unknown | 157 (4.8) | 0 | 157 (4.8) |
| Chronic graft-versus-host disease, no. (%) | |||
| No | 2366 (70.9) | 33 (63.5) | 2333 (71.0) |
| Yes | 913 (27.4) | 15 (28.9) | 898 (27.3) |
| Unknown | 58 (1.7) | 4 (7.6) | 54 (1.7) |
| Characteristic . | All patients . | Patients with breast cancer . | Patients without breast cancer . |
|---|---|---|---|
| Patients, no. | 3337 | 52 | 3285 |
| Median age at transplantation, y (range) | 28.1 (0.2-70.3) | 32.9 (3.6-59.2) | 28.0 (0.2-70.3) |
| Median age at breast cancer, y (range) | N/A | 47.5 (25.5-65.8) | NA |
| Location of transplant center, no. (%) | |||
| EBMT | 2369 (71.0) | 29 (55.8) | 2340 (71.2) |
| FHCRC | 968 (29.1) | 23 (44.2) | 945 (28.8) |
| Age at HCT, no. (%) | |||
| Younger than 10 y | 549 (16.5) | 1 (1.9) | 548 (16.7) |
| 10 to 17 y | 477 (14.3) | 7 (13.5) | 470 (14.3) |
| 18 to 39 y | 1577 (47.2) | 25 (48.1) | 1552 (47.3) |
| 40 y or older | 734 (22.0) | 19 (36.5) | 715 (21.7) |
| Primary disease, no. (%) | |||
| Acute leukemia | 1364 (40.9) | 22 (42.3) | 1342 (40.9) |
| Chronic leukemia | 1060 (34.8) | 22 (42.3) | 1038 (31.6) |
| Myelodysplastic syndrome | 200 (6.0) | 1 (1.9) | 199 (6.1) |
| Multiple myeloma & plasma cell disorders | 52 (1.6) | 0 (0) | 52 (1.6) |
| Lymphoma | 94 (2.8) | 4 (7.7) | 90 (2.7) |
| Solid tumors | 7 (0.2) | 0 (0) | 7 (1.2) |
| Total body radiation (TBI), no. (%) | |||
| No | 1070 (32.1) | 5 (9.6) | 1065 (32.4) |
| Yes | 2162 (64.8) | 47 (90.4) | 2115 (64.4) |
| Unknown | 105 (3.1) | 0 | 105 (3.2) |
| Donor type, no. (%) | |||
| HLA-identical related | 2645 (79.3) | 43 (82.7) | 2602 (79.2) |
| HLA-mismatched related | 169 (5.0) | 3 (5.8) | 166 (5.0) |
| Unrelated | 494 (14.8) | 6 (11.5) | 488 (14.9) |
| Unknown | 29 (0.9) | 0 | 29 (0.9) |
| Acute graft-versus-host disease, no. (%) | |||
| None | 1142 (34.2) | 20 (38.5) | 1122 (34.2) |
| Grades 1 to 2 | 1723 (51.6) | 27 (51.9) | 1696 (51.6) |
| Grades 3 to 4 | 315 (9.4) | 5 (9.6) | 310 (9.4) |
| Unknown | 157 (4.8) | 0 | 157 (4.8) |
| Chronic graft-versus-host disease, no. (%) | |||
| No | 2366 (70.9) | 33 (63.5) | 2333 (71.0) |
| Yes | 913 (27.4) | 15 (28.9) | 898 (27.3) |
| Unknown | 58 (1.7) | 4 (7.6) | 54 (1.7) |