Multivariate Cox regression analyses of OS
| Parameter . | 263 patients . | 175 patients . | P . | |
|---|---|---|---|---|
| HR (95% CI)* . | P . | HR (95% CI)* . | ||
| CD49d less than 30% | 3.72 (1.62-8.56) | .002 | 3.52 (1.22-10.2) | .02 |
| ZAP-70 more than 20% | 3.32 (1.46-7.51) | .009 | — | — |
| Age more than 65 years | 3.73 (1.63-8.51) | .002 | 6.85 (2.54-18.5) | .001 |
| IGHV UM | NT | NT | 6.53 (2.32-18.4) | .001 |
| Parameter . | 263 patients . | 175 patients . | P . | |
|---|---|---|---|---|
| HR (95% CI)* . | P . | HR (95% CI)* . | ||
| CD49d less than 30% | 3.72 (1.62-8.56) | .002 | 3.52 (1.22-10.2) | .02 |
| ZAP-70 more than 20% | 3.32 (1.46-7.51) | .009 | — | — |
| Age more than 65 years | 3.73 (1.63-8.51) | .002 | 6.85 (2.54-18.5) | .001 |
| IGHV UM | NT | NT | 6.53 (2.32-18.4) | .001 |
Multivariate Cox regression analyses of OS were performed by including the following covariates: CD49d, CD38, ZAP-70, age (263 patients) or CD49d, CD38, ZAP-70, age, and IGHV (175 patients). For each variable, the selected cutoff points or the compared categories are indicated.
OS indicates overall survival; HR, hazard ratio; CI, confidence interval; NT, not tested; other abbreviations are as in Table 1.
Based on the final model after stepwise selection of covariates.