Patient characteristics according to their tertile frequency distribution over time to MDS-CA
| Variable . | 1st tertile . | 2nd tertile . | 3rd tertile . | P* . |
|---|---|---|---|---|
| TT2 or TT3 protocol | 4/35 (11) | 9/35 (26) | 14/35 (40) | .006 |
| More than 12 mo from diagnosis | 16/35 (46) | 7/35 (20) | 6/35 (17) | .008 |
| 1st quartile of platelets, 109/L | 11/31 (35) | 4/32 (13) | 3/33 (9) | .007 |
| CRP concentration 6.0 mg/L or more | 15/30 (50) | 10/31 (32) | 5/27 (19) | .012 |
| CD34 infused with 2nd transplantation less than 3×106/kg | 6/16 (38) | 2/21 (10) | 2/17 (12) | .061 |
| LDH level 190 U/L or more | 6/31 (19) | 11/32 (34) | 4/33 (12) | .461 |
| −7/7q−; −5/5q−;del(20q);+8 | 27/35 (77) | 27/35 (77) | 20/35 (57) | .067 |
| −7/7q− or del(20q) | 22/35 (63) | 17/35 (49) | 13/35 (37) | .030* |
| Variable . | 1st tertile . | 2nd tertile . | 3rd tertile . | P* . |
|---|---|---|---|---|
| TT2 or TT3 protocol | 4/35 (11) | 9/35 (26) | 14/35 (40) | .006 |
| More than 12 mo from diagnosis | 16/35 (46) | 7/35 (20) | 6/35 (17) | .008 |
| 1st quartile of platelets, 109/L | 11/31 (35) | 4/32 (13) | 3/33 (9) | .007 |
| CRP concentration 6.0 mg/L or more | 15/30 (50) | 10/31 (32) | 5/27 (19) | .012 |
| CD34 infused with 2nd transplantation less than 3×106/kg | 6/16 (38) | 2/21 (10) | 2/17 (12) | .061 |
| LDH level 190 U/L or more | 6/31 (19) | 11/32 (34) | 4/33 (12) | .461 |
| −7/7q−; −5/5q−;del(20q);+8 | 27/35 (77) | 27/35 (77) | 20/35 (57) | .067 |
| −7/7q− or del(20q) | 22/35 (63) | 17/35 (49) | 13/35 (37) | .030* |
Results are shown as n/N (%), where n indicates number with factor and N indicates number with valid data for factor. Nonsignificant variables include female, white, age, kappa light chain, hemoglobin level, creatinine level, albumin concentration, B2M concentration, cytogenetic abnormalities, second transplantation, 3 or more transplantations, months between first therapy to first transplantation, months between first and second transplantations, total CD34 collected prior to first transplantation, days of CD34 harvest, platelet recovery approximately 3 months after first and second transplantations.
Cochran-Armitage trend test.