Results of the 4 included studies investigating FDG-PET/CT fusion
| HD/NHL . | Study, year . | Scoring system . | Initial staging . | Restaging . | ||
|---|---|---|---|---|---|---|
| Sensitivity, % (95% CI) | Specificity, % (95% CI) | Sensitivity, % (95% CI) | Specificity, % (95% CI) | |||
| HD | Schaefer et al,55 2007 | Patient-based analysis | — | — | 100 (85.7-100) † | 90.7 (78.4-96.3) † |
| Mixed | La Fougere et al,39 2006 | Region-based analysis; (7 predefined regions) | 97.9 (89.1-99.6) *; 100 (87.5-100) † | 100 (97.7-100) *; 100 (93.7-100) † | 96.4 (82.3-99.4) *; 97.3 (90.8-99.3) † | 100 (97.8-100) *; 99.5% (97.1-99.9) † |
| Mixed | Rhodes et al,56 2006 | Patient-based analysis | — | — | 94.7 (75.4-99.1) ‡ | 90.6 (85.3-94.1) ‡ |
| Mixed | Freudenberg et al,49 2004 | Region-based analysis; (5 predefined regions) | — | — | 91.3 (73.2-97.6) *; 95.7 (79.0-99.2) † | 99.1 (95.1-99.8) *; 99.1 (95.1-99.8) † |
| Mixed | Freudenberg et al,49 2004 | Patient-based analysis | — | — | 92.9 (68.5-98.7) *; 92.9 (68.5-98.7) † | 10 (77.2-100) *,100 (77.2-100) † |
| HD/NHL . | Study, year . | Scoring system . | Initial staging . | Restaging . | ||
|---|---|---|---|---|---|---|
| Sensitivity, % (95% CI) | Specificity, % (95% CI) | Sensitivity, % (95% CI) | Specificity, % (95% CI) | |||
| HD | Schaefer et al,55 2007 | Patient-based analysis | — | — | 100 (85.7-100) † | 90.7 (78.4-96.3) † |
| Mixed | La Fougere et al,39 2006 | Region-based analysis; (7 predefined regions) | 97.9 (89.1-99.6) *; 100 (87.5-100) † | 100 (97.7-100) *; 100 (93.7-100) † | 96.4 (82.3-99.4) *; 97.3 (90.8-99.3) † | 100 (97.8-100) *; 99.5% (97.1-99.9) † |
| Mixed | Rhodes et al,56 2006 | Patient-based analysis | — | — | 94.7 (75.4-99.1) ‡ | 90.6 (85.3-94.1) ‡ |
| Mixed | Freudenberg et al,49 2004 | Region-based analysis; (5 predefined regions) | — | — | 91.3 (73.2-97.6) *; 95.7 (79.0-99.2) † | 99.1 (95.1-99.8) *; 99.1 (95.1-99.8) † |
| Mixed | Freudenberg et al,49 2004 | Patient-based analysis | — | — | 92.9 (68.5-98.7) *; 92.9 (68.5-98.7) † | 10 (77.2-100) *,100 (77.2-100) † |
— indicates no entry.
*Side-by-side assessment of separately obtained CT and FDG-PET images.
†Hardware-oriented approach to image fusion; combined PET/CT.
‡Both * and † were available.