Table 7

Characteristics of the 4 included studies investigating FDG-PET/CT fusion

HD/NHLStudy, yearPatients/scans, no.Median age, (range)Sex, M/FCriteria for positivityInterpreter(s)
HD Schaefer et al,55  2007 66/66 35.2 (11-76) 46/20 NR Two board-certified nuclear medicine physicians (6 and 3 years of PET experience) and 2 board-certified radiologists (10 and 6 years of CT experience) 
Mixed La Fougere et al,39  2006 100/100 NR (29-70) 40/10 A combination of the criteria mentioned in Tables 5 and 6 for this study Two board-certified radiologists and nuclear medicine specialists with more than 10 years of experience in CT and PET 
Mixed Rhodes et al,56  2006 41/247 13 (3-18) 23/18 Nonphysiologic focal FDG uptake; FDG uptake equal to or greater than that seen in the liver corresponding to a lymph node or abnormality on simultaneously performed diagnostic CT scan NR 
Mixed Freudenberg et al,49  2004 27/27 46* (19-70) 16/11 A SUVmax ≥2.5 in an area of focal tracer uptake and lymph nodes with a diameter >15 mm in the groin or >10 mm in all other regions Two experienced nuclear medicine physicians and radiologists 
HD/NHLStudy, yearPatients/scans, no.Median age, (range)Sex, M/FCriteria for positivityInterpreter(s)
HD Schaefer et al,55  2007 66/66 35.2 (11-76) 46/20 NR Two board-certified nuclear medicine physicians (6 and 3 years of PET experience) and 2 board-certified radiologists (10 and 6 years of CT experience) 
Mixed La Fougere et al,39  2006 100/100 NR (29-70) 40/10 A combination of the criteria mentioned in Tables 5 and 6 for this study Two board-certified radiologists and nuclear medicine specialists with more than 10 years of experience in CT and PET 
Mixed Rhodes et al,56  2006 41/247 13 (3-18) 23/18 Nonphysiologic focal FDG uptake; FDG uptake equal to or greater than that seen in the liver corresponding to a lymph node or abnormality on simultaneously performed diagnostic CT scan NR 
Mixed Freudenberg et al,49  2004 27/27 46* (19-70) 16/11 A SUVmax ≥2.5 in an area of focal tracer uptake and lymph nodes with a diameter >15 mm in the groin or >10 mm in all other regions Two experienced nuclear medicine physicians and radiologists 

*Indicates a mean age.

HD indicates Hodgkin disease; NHL, non-Hodgkin lymphoma; and NR, not reported.

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