Cotswold-modified Ann Arbor classification
| . | Involvement/features . |
|---|---|
| Stage | |
| I | Single lymph node region (I) or one extralymphatic site (IE) |
| II | Two or more lymph node regions, same side of the diaphragm (II) or local extralymphatic extension plus one or more lymph node regions same side of the diaphragm (IIE) |
| III | Lymph node regions on both sides of the diaphragm (III), which may be accompanied by local extralymphatic extension (IIIE) |
| IV | Diffuse involvement of one or more extralymphatic organs or sites |
| Suffix | |
| A | No B symptoms |
| B | Presence of at least one of the following: unexplained weight loss >10% baseline during 6 months before staging; recurrent unexplained fever >38°C; recurrent night sweats |
| X | Bulky tumor is defined as either a single mass of tumor tissue exceeding 10 cm in largest diameter or a mediastinal mass exceeding one-third of the maximum transverse transthoracic diameter measured on a standard posterior-anterior chest radiograph |
| . | Involvement/features . |
|---|---|
| Stage | |
| I | Single lymph node region (I) or one extralymphatic site (IE) |
| II | Two or more lymph node regions, same side of the diaphragm (II) or local extralymphatic extension plus one or more lymph node regions same side of the diaphragm (IIE) |
| III | Lymph node regions on both sides of the diaphragm (III), which may be accompanied by local extralymphatic extension (IIIE) |
| IV | Diffuse involvement of one or more extralymphatic organs or sites |
| Suffix | |
| A | No B symptoms |
| B | Presence of at least one of the following: unexplained weight loss >10% baseline during 6 months before staging; recurrent unexplained fever >38°C; recurrent night sweats |
| X | Bulky tumor is defined as either a single mass of tumor tissue exceeding 10 cm in largest diameter or a mediastinal mass exceeding one-third of the maximum transverse transthoracic diameter measured on a standard posterior-anterior chest radiograph |