Genes differentially expressed in the presence of EBV in L591 and KM-H2 cell lines
| Gene symbol . | Gene name . | Accession no. . | Mean fold change (L591) . | Mean fold change (KM-H2) . | Ontology . |
|---|---|---|---|---|---|
| CYP1B1 | Cytochrome P450, family 1, subfamily B, polypeptide 1 | NM_000104 | 9.32 | 2.55 | Electron transport |
| ID2 | Inhibitor of DNA binding 2 | NM_002166 | 4.84 | 1.98 | Inhibitor of DNA binding and differentiation |
| CR2 | Complement component (3d/Epstein Barr virus) receptor 2 | NM_001877 | 4.24 | 2.02 | Immune response |
| CXCR4 | Chemokine (C-X-C motif) receptor 4 | AJ224869 | 4.10 | 2.80 | Immune response, chemotaxis, GPCR protein signaling pathway |
| ZFAND5 | Zinc finger, AN1-type domain 5 | AF062347 | 3.54 | 1.75 | DNA and zinc ion binding |
| CRYZ | Crystallin, zeta (quinone reductase) | NM_001889 | 3.49 | 1.50 | Visual perception |
| ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | L35594 | 3.10 | 4.16 | Cell motility, GPCR protein signaling pathway |
| TJP2 | Tight junction protein 2 (zona occludens 2) | NM_004817 | 2.93 | 1.76 | Protein binding at cell-cell junctions |
| GLUL | Glutamate-ammonia ligase (glutamine synthetase) | AL161952 | 2.89 | 3.33 | Glutamine biosynthesis |
| CCL20 | Chemokine (C-C motif) ligand 20 | NM_004591 | 2.40 | 2.77 | Immune response, chemotaxis, cell-cell signaling |
| HSPA1A/B | Heat shock 70kDa protein 1A or 1B | NM_005345 | 1.64 | 2.70 | Ubiquitin-proteasome pathway, protein folding, signal transduction |
| TNFSF9 | Tumor necrosis factor (ligand) superfamily, member 9 | NM_003811 | 1.59 | 1.87 | Apoptosis, cell proliferation, cell-cell signaling, immune response |
| IFI27 | Interferon, alpha-inducible protein 27 | NM_005532 | −1.60 | −19.38 | Immune response |
| PTPRK | Protein tyrosine phosphatase, receptor type, K | NM_002844 | −2.31 | −2.99 | Protein amino acid dephosphorylation |
| Gene symbol . | Gene name . | Accession no. . | Mean fold change (L591) . | Mean fold change (KM-H2) . | Ontology . |
|---|---|---|---|---|---|
| CYP1B1 | Cytochrome P450, family 1, subfamily B, polypeptide 1 | NM_000104 | 9.32 | 2.55 | Electron transport |
| ID2 | Inhibitor of DNA binding 2 | NM_002166 | 4.84 | 1.98 | Inhibitor of DNA binding and differentiation |
| CR2 | Complement component (3d/Epstein Barr virus) receptor 2 | NM_001877 | 4.24 | 2.02 | Immune response |
| CXCR4 | Chemokine (C-X-C motif) receptor 4 | AJ224869 | 4.10 | 2.80 | Immune response, chemotaxis, GPCR protein signaling pathway |
| ZFAND5 | Zinc finger, AN1-type domain 5 | AF062347 | 3.54 | 1.75 | DNA and zinc ion binding |
| CRYZ | Crystallin, zeta (quinone reductase) | NM_001889 | 3.49 | 1.50 | Visual perception |
| ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | L35594 | 3.10 | 4.16 | Cell motility, GPCR protein signaling pathway |
| TJP2 | Tight junction protein 2 (zona occludens 2) | NM_004817 | 2.93 | 1.76 | Protein binding at cell-cell junctions |
| GLUL | Glutamate-ammonia ligase (glutamine synthetase) | AL161952 | 2.89 | 3.33 | Glutamine biosynthesis |
| CCL20 | Chemokine (C-C motif) ligand 20 | NM_004591 | 2.40 | 2.77 | Immune response, chemotaxis, cell-cell signaling |
| HSPA1A/B | Heat shock 70kDa protein 1A or 1B | NM_005345 | 1.64 | 2.70 | Ubiquitin-proteasome pathway, protein folding, signal transduction |
| TNFSF9 | Tumor necrosis factor (ligand) superfamily, member 9 | NM_003811 | 1.59 | 1.87 | Apoptosis, cell proliferation, cell-cell signaling, immune response |
| IFI27 | Interferon, alpha-inducible protein 27 | NM_005532 | −1.60 | −19.38 | Immune response |
| PTPRK | Protein tyrosine phosphatase, receptor type, K | NM_002844 | −2.31 | −2.99 | Protein amino acid dephosphorylation |
Only genes that met the following criteria were included; a fold change equal to or greater than 1.5, a false discovery rate of less than or equal to 10%.