Cytotoxicity of E9(Fv)-PE38 on B-NHL cell lines
| Cell lines . | IC50, ng/mL . | MFI . |
|---|---|---|
| Burkitt lymphoma | ||
| BL2 | 19 | 127 |
| BL60 | 30 | 33 |
| BL74 | 30 | 29 |
| BL104 | 8.0 | 195 |
| Daudi | 90 | 48 |
| KEM I | 600 | 55 |
| Ramos | 16 | 159 |
| DLBCL | ||
| OCI-Ly7 | 50 | 76 |
| REC1 | 1.0 | 243 |
| SU-DHL-6 | 18 | 149 |
| Other B-NHL | ||
| DOHH2 | 8.2 | 130 |
| NU-DUL-1 | 30 | 80 |
| AS283A | >1000 | — |
| CRO-AP2 | >1000 | — |
| Granta-519 | >1000 | — |
| Cell lines . | IC50, ng/mL . | MFI . |
|---|---|---|
| Burkitt lymphoma | ||
| BL2 | 19 | 127 |
| BL60 | 30 | 33 |
| BL74 | 30 | 29 |
| BL104 | 8.0 | 195 |
| Daudi | 90 | 48 |
| KEM I | 600 | 55 |
| Ramos | 16 | 159 |
| DLBCL | ||
| OCI-Ly7 | 50 | 76 |
| REC1 | 1.0 | 243 |
| SU-DHL-6 | 18 | 149 |
| Other B-NHL | ||
| DOHH2 | 8.2 | 130 |
| NU-DUL-1 | 30 | 80 |
| AS283A | >1000 | — |
| CRO-AP2 | >1000 | — |
| Granta-519 | >1000 | — |
MFI indicates median fluorescence intensity; DLBCL, diffuse large B-cell lymphoma; B-NHL, B-cell non-Hodgkin lymphoma; and —, not applicable.