Simplified prognostic index
| Points . | Age, y . | ECOG . | LDHULN . | WBC, 109/L . |
|---|---|---|---|---|
| 0 | <50 | 0-1 | <0.67 | < 6.700 |
| 1 | 50-59 | — | 0.67-0.99 | 6.700-9.999 |
| 2 | 60-69 | 2-4 | 1.000 -1.49 | 1.000-14.999 |
| 3 | ≥70 | — | ≥1.5000 | ≥15000 |
| Points . | Age, y . | ECOG . | LDHULN . | WBC, 109/L . |
|---|---|---|---|---|
| 0 | <50 | 0-1 | <0.67 | < 6.700 |
| 1 | 50-59 | — | 0.67-0.99 | 6.700-9.999 |
| 2 | 60-69 | 2-4 | 1.000 -1.49 | 1.000-14.999 |
| 3 | ≥70 | — | ≥1.5000 | ≥15000 |
For each prognostic factor, 0 to 3 points were given to each patient and points were summed up to a maximum of 11. Patients with 0 to 3 points in summary were classified as low risk, patients with 4 to 5 points as intermediate risk, and patients with 6 to 11 points as high risk. ECOG performance status was weighted with 2 points if patients were unable to work or bedridden (ECOG 2-4). LDH was weighted according to the ratio to the ULN. Thus, for an ULN of 240 U/L, the cutpoints were 180 U/L, 240 U/L, and 360 U/L, for example.
— indicates not applicable.