Independent prognostic factors for overall survival identified by backward variable selection with multiple Cox regression on significance level 5% for the Wald statistic
| Prognostic factor . | Comparison . | β . | SE . | RR . | 95% LCL . | 95% UCL . | P . |
|---|---|---|---|---|---|---|---|
| Age | 1 year older | 0.03535 | 0.009604 | 1.04 | 1.02 | 1.06 | <.001 |
| ECOG | 2-4 vs 0-1 | 0.6978 | 0.2663 | 2.01 | 1.19 | 3.39 | .009 |
| LDH | 10-fold | 1.367 | 0.4962 | 3.92 | 1.48 | 10.37 | .006 |
| WBC count | 10-fold | 0.9393 | 0.2220 | 2.56 | 1.66 | 3.95 | <.001 |
| Prognostic factor . | Comparison . | β . | SE . | RR . | 95% LCL . | 95% UCL . | P . |
|---|---|---|---|---|---|---|---|
| Age | 1 year older | 0.03535 | 0.009604 | 1.04 | 1.02 | 1.06 | <.001 |
| ECOG | 2-4 vs 0-1 | 0.6978 | 0.2663 | 2.01 | 1.19 | 3.39 | .009 |
| LDH | 10-fold | 1.367 | 0.4962 | 3.92 | 1.48 | 10.37 | .006 |
| WBC count | 10-fold | 0.9393 | 0.2220 | 2.56 | 1.66 | 3.95 | <.001 |
The candidate prognostic factors included were age, sex, ECOG performance status, Ann Arbor stage, B-symptoms, number of extranodal sites, number of nodal areas, WBC count, platelet count, LDH, and hemoglobin. The model was developed using 409 complete cases for the candidate prognostic factors. The same model was identified using forward variable selection or a significance level of 10%.
β indicates the regression coefficient; SE, standard error; RR, relative risk; LCL, lower confidence limit; and UCL, upper confidence limit.