Table 3 Laboratory parameters monitored... | American Society of Hematology

Table 3

Laboratory parameters monitored for immune recovery

Time after transplantation	Patients younger than 50 y, n = 33	Patients 50 y or older, n = 19	All, n = 52
5 to 7 mo., no. evaluated/eligible	24/27	16/17	40/44
CD4, %
200 or more cells/μL	38	44	40
Less than 100 cells/μL	25	13	20
PHA, %
Median	52	13	32
Less than 25% LLN	33	69	48*
11 to 12 mo., no. evaluated/eligible	21/24	11/13	32/35
CD4, %
200 or more cells/μL	71	55	66
Less than 100 cells/μL	10	9	9
PHA, %
Median	113	14	71
Less than 25% LLN	0	64	22†
15 to 18 mo., no. evaluated/eligible	17/23	10/10	27/33
CD4, %
200 or more cells/μL	71	90	82
Less than 100 cells/μL	0	0	0
PHA, %
Median	129	37	100
Less than 25% LLN	6	44	20*
24 mo., no. evaluated/eligible	12/21	4/7	16/28
CD4, %
200 or more cells/μL	83	75	81
Less than 100 cells/μL	8	0	6
PHA, %
Median	126	22	103
Less than 25% LLN	9	50	20‡

Time after transplantation	Patients younger than 50 y, n = 33	Patients 50 y or older, n = 19	All, n = 52
5 to 7 mo., no. evaluated/eligible	24/27	16/17	40/44
CD4, %
200 or more cells/μL	38	44	40
Less than 100 cells/μL	25	13	20
PHA, %
Median	52	13	32
Less than 25% LLN	33	69	48*
11 to 12 mo., no. evaluated/eligible	21/24	11/13	32/35
CD4, %
200 or more cells/μL	71	55	66
Less than 100 cells/μL	10	9	9
PHA, %
Median	113	14	71
Less than 25% LLN	0	64	22†
15 to 18 mo., no. evaluated/eligible	17/23	10/10	27/33
CD4, %
200 or more cells/μL	71	90	82
Less than 100 cells/μL	0	0	0
PHA, %
Median	129	37	100
Less than 25% LLN	6	44	20*
24 mo., no. evaluated/eligible	12/21	4/7	16/28
CD4, %
200 or more cells/μL	83	75	81
Less than 100 cells/μL	8	0	6
PHA, %
Median	126	22	103
Less than 25% LLN	9	50	20‡

CD4 indicates the percentage of patients with an absolute CD4 count 200 or more or less than 100 cells/μL.

Each patient's PHA response was calculated as percentage = (patient response/LLN).

Less than 25% LLN indicates the percentage of patients with PHA responses less than 25% LLN.

P = .05

P < .01

P = .14