Outcome parameters of transplantation
Outcome . | No. . |
---|---|
Median follow-up (range), mo | 45 (15.5-66.3) |
Engraftment | 51 (evaluable) |
Median transplant dose CD34+ × 106/kg (range) | 5.75 (0.37-23.9) |
Median transplant dose CD3+ × 103/kg (range) | 0.99 (0-297) |
Patients engrafting neutrophils | 51/51 |
Median days to ANC 0.5 × 109/L or more (range) | 11 (9-22) |
Patients engrafting platelets | 47/51 |
Median days to platelets 20 × 109/L or more (range) | 16 (13-54) |
Posttransplantation EBV-LPD | 2 |
GvHD | 8 |
Acute, grades II-IV | 4/49; 4 overall grade 2 |
Chronic | 4/43; 1 limited; 3 extensive |
Relapses | 9 |
AML CR1 | 2 |
AML, 2° MDS | 3 |
ALL CR1 Ph+ | 1 |
ALL CR2 | 1 |
NHL | 2 |
Deaths | 19 |
Cause of death | |
Relapse | 8 |
AML CRI after MDS | 3 |
AML CR1 | 2 |
ALL CR2 | 1 |
Burkitt lymphoma, PR | 1 |
Diffuse large cell lymphoma, PR | 1 |
Infection | 8 |
GVHD and secondary complications | 2 |
Other, complications of VATS | 1 |
Outcome . | No. . |
---|---|
Median follow-up (range), mo | 45 (15.5-66.3) |
Engraftment | 51 (evaluable) |
Median transplant dose CD34+ × 106/kg (range) | 5.75 (0.37-23.9) |
Median transplant dose CD3+ × 103/kg (range) | 0.99 (0-297) |
Patients engrafting neutrophils | 51/51 |
Median days to ANC 0.5 × 109/L or more (range) | 11 (9-22) |
Patients engrafting platelets | 47/51 |
Median days to platelets 20 × 109/L or more (range) | 16 (13-54) |
Posttransplantation EBV-LPD | 2 |
GvHD | 8 |
Acute, grades II-IV | 4/49; 4 overall grade 2 |
Chronic | 4/43; 1 limited; 3 extensive |
Relapses | 9 |
AML CR1 | 2 |
AML, 2° MDS | 3 |
ALL CR1 Ph+ | 1 |
ALL CR2 | 1 |
NHL | 2 |
Deaths | 19 |
Cause of death | |
Relapse | 8 |
AML CRI after MDS | 3 |
AML CR1 | 2 |
ALL CR2 | 1 |
Burkitt lymphoma, PR | 1 |
Diffuse large cell lymphoma, PR | 1 |
Infection | 8 |
GVHD and secondary complications | 2 |
Other, complications of VATS | 1 |
EBV-LPD indicates Epstein-Barr virus lymphoproliferative disease; GvHD, graft-versus-host disease; PR, partial remission; and VATS, video-assisted thoracic surgery.