Table 3

Altered glutamine and glutathione precursors in plasma of SCD patients compared with healthy volunteers

GSH precursors (μM)Plasma
ControlsSCDP
Glutamate 9 ± 2 18 ± 2 .006* 
Cysteine 238 ± 15 267 ± 16 .4 
Glycine 32 ± 4 53 ± 4 .01 
Glutamine 708 ± 60 825 ± 55 .3 
GSH precursors (μM)Plasma
ControlsSCDP
Glutamate 9 ± 2 18 ± 2 .006* 
Cysteine 238 ± 15 267 ± 16 .4 
Glycine 32 ± 4 53 ± 4 .01 
Glutamine 708 ± 60 825 ± 55 .3 

Data are shown as average plus or minus SEM.

*

Unpaired t test performed with Welch correction for unequal variance.

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