Influence of chemotherapy on CK18F
Day . | HD-autologous, n=18 . | HD/intermediate-allogeneic, n=16 . | Mini-allogeneic, n=7 . | |||
---|---|---|---|---|---|---|
Mean (95% CI) . | P . | Mean (95% CI) . | P . | Mean (95% CI) . | P . | |
Baseline, before chemotherapy | 171 (147-198) | NA | 179 (158-203) | NA | 203 (131-314) | NA |
Day 0, day of SCT | 289 (239-349) | <.001 | 268 (221-325) | <.001 | 295 (174-500) | .26 |
Days 6 to 9 after SCT | 222 (197-250) | .01 | 192 (165-223) | .24 | 172 (103-286) | .36 |
Days 12 to 24 after SCT | 199 (179-220) | .03 | 224 (184-273) | .008 | 249 (177-350) | .21 |
Day . | HD-autologous, n=18 . | HD/intermediate-allogeneic, n=16 . | Mini-allogeneic, n=7 . | |||
---|---|---|---|---|---|---|
Mean (95% CI) . | P . | Mean (95% CI) . | P . | Mean (95% CI) . | P . | |
Baseline, before chemotherapy | 171 (147-198) | NA | 179 (158-203) | NA | 203 (131-314) | NA |
Day 0, day of SCT | 289 (239-349) | <.001 | 268 (221-325) | <.001 | 295 (174-500) | .26 |
Days 6 to 9 after SCT | 222 (197-250) | .01 | 192 (165-223) | .24 | 172 (103-286) | .36 |
Days 12 to 24 after SCT | 199 (179-220) | .03 | 224 (184-273) | .008 | 249 (177-350) | .21 |
CK18F means and 95% CI values are in U/L. P values of paired t test are in comparison with baseline (before chemotherapy).
NA indicates not applicable; HD-autologous, high-dose melphalan and autologous SCT; HD/intermediate-allogeneic, all chemotherapy conditioning regimen followed by allogeneic SCT except 2 Gy TBI+/-Fludarabin+/-ATG; and mini-allogeneic, 2 Gy TBI+/-Fludarabin+/-ATG followed by allogeneic SCT.