Table 6 Correlation of TP53 mutation and... | American Society of Hematology

Table 6

Correlation of TP53 mutation and 17p13.1 deletion with TP53 and CDKN1A mRNA expression

	TP53 mRNA expression	CDKN1A mRNA expression
TP53 mutation (n = 24)	0.62	0.53
Wild-type TP53 (n = 89)*	0.81	0.70
P	<.001	.001
17p13.1 deletion (n = 26)	0.58	0.55
17p13.1 wild-type (n = 106)†	0.88	0.68
P	<.001	.058

	TP53 mRNA expression	CDKN1A mRNA expression
TP53 mutation (n = 24)	0.62	0.53
Wild-type TP53 (n = 89)*	0.81	0.70
P	<.001	.001
17p13.1 deletion (n = 26)	0.58	0.55
17p13.1 wild-type (n = 106)†	0.88	0.68
P	<.001	.058

Expression is stated as median values for all table entries.

Wild-type is defined as normal results in the dHPLC screening assay.

Wild-type is defined as normal results in the FISH assay.