SNPs from genes with a P value of .001 or less from the logistic regression or haplotype analyses
Gene*, SNP . | SNP results . | |||||
---|---|---|---|---|---|---|
Alleles . | MAF patients . | MAF controls . | P . | OR† (95% CI) . | SNPs in LR‡ . | |
CREB1 | ||||||
rs2551640 | A/G | 0.37 | 0.31 | .009 | 1.30 (1.07, 1.59) | — |
rs2709359 | G/A | 0.021 | 0.037 | .03 | 0.54 (0.30, 0.95) | — |
rs2709360 | T/C | 0.022 | 0.037 | .05 | 0.57 (0.32, 1.00) | × |
rs2709402 | C/A | 0.17 | 0.22 | .004 | 0.70 (0.56, 0.89) | × |
rs10932201 | G/A | 0.47 | 0.46 | 1.0 | 1.00 (0.83, 1.20) | × |
rs2551919 | C/T | 0.17 | 0.22 | .002 | 0.69 (0.55, 0.88) | — |
rs3770704 | T/C | 0.016 | 0.009 | .2 | 1.70 (0.73, 3.94) | × |
FGG | ||||||
rs1800792 | A/G | 0.51 | 0.42 | .0002 | 1.44 (1.19, 1.73) | × |
MAP3K5 | ||||||
rs2327742 | A/G | 0.19 | 0.14 | .004 | 1.44 (1.12, 1.84) | — |
rs13203080 | G/A | 0.13 | 0.14 | .2 | 0.85 (0.64, 1.11) | — |
rs7755097 | T/C | 0.18 | 0.14 | .02 | 1.35 (1.05, 1.74) | × |
rs2327743 | T/C | 0.20 | 0.14 | .002 | 1.48 (1.16, 1.89) | — |
rs2076262 | T/C | 0.02 | 0.00 | .01 | 4.06 (1.34, 12.3) | × |
rs12164028 | A/G | 0.02 | 0.01 | .02 | 3.08 (1.23, 7.71) | × |
rs2064205 | C/T | 0.38 | 0.38 | .9 | 1.01 (0.84, 1.22) | — |
rs6906871 | A/C | 0.38 | 0.37 | .7 | 1.03 (0.86, 1.24) | — |
rs2237269 | G/C | 0.16 | 0.17 | .4 | 0.91 (0.71, 1.16) | × |
rs6904753 | C/T | 0.19 | 0.19 | 1.0 | 0.99 (0.79, 1.24) | — |
rs3765259 | C/T | 0.53 | 0.48 | .08 | 1.17 (0.98, 1.39) | × |
rs9402839 | G/A | 0.10 | 0.11 | .5 | 0.89 (0.65, 1.22) | — |
rs4363056 | T/C | 0.42 | 0.38 | .09 | 1.18 (0.98, 1.42) | — |
rs7753357 | T/A | 0.07 | 0.09 | .05 | 0.71 (0.51, 1.00) | — |
rs7748892 | A/G | 0.04 | 0.04 | 1.0 | 1.01 (0.63, 1.62) | × |
rs6570087 | C/A | 0.03 | 0.04 | .3 | 0.74 (0.42, 1.27) | × |
rs10484491 | A/G | 0.49 | 0.46 | .3 | 1.10 (0.91, 1.32) | × |
rs4896219 | A/C | 0.48 | 0.48 | .9 | 1.02 (0.85, 1.22) | × |
rs932589 | G/A | 0.40 | 0.41 | .6 | 0.95 (0.78, 1.15) | × |
rs9402845 | G/A | 0.38 | 0.39 | .9 | 0.98 (0.82, 1.18) | × |
rs1570054 | C/T | 0.36 | 0.38 | .4 | 0.91 (0.75, 1.11) | × |
RIPK3 | ||||||
rs3212254 | C/A | 0.04 | 0.07 | .004 | 0.55 (0.37, 0.82) | × |
rs724165 | A/G | 0.40 | 0.44 | 0.1 | 0.87 (0.72, 1.05) | × |
rs3212247 | T/C | 0.06 | 0.08 | 0.1 | 0.75 (0.52, 1.07) | — |
rs3212243 | A/G | 0.28 | 0.24 | 0.07 | 1.22 (0.99, 1.50) | × |
LSP1 | ||||||
rs2089910 | C/T | 0.26 | 0.19 | .0005 | 1.49 (1.19, 1.86) | × |
rs3817197 | G/A | 0.50 | 0.47 | 0.2 | 1.13 (0.93, 1.36) | × |
TRAF1 | ||||||
rs4836834 | A/T | 0.45 | 0.41 | .03 | 1.22 (1.02, 1.47) | × |
rs2269059 | T/A | 0.11 | 0.065 | .0007 | 1.78 (1.28, 2.48) | × |
rs1930781 | A/G | 0.34 | 0.34 | .8 | 1.02 (0.84, 1.24) | — |
rs3761846 | T/C | 0.45 | 0.40 | .02 | 1.24 (1.03, 1.50) | — |
rs2416806 | C/G | 0.34 | 0.33 | .8 | 1.03 (0.85, 1.25) | — |
DUSP2 | ||||||
rs1724120 | G/A | 0.37 | 0.44 | .001 | 0.74 (0.61, 0.89) | × |
ITGB3 | ||||||
rs2317385 | C/T | 0.16 | 0.18 | .6 | 0.93 (0.73, 1.19) | — |
rs2056131 | C/T | 0.34 | 0.30 | .1 | 1.17 (0.96, 1.42) | × |
rs4525555 | C/T | 0.31 | 0.34 | .1 | 0.87 (0.72, 1.05) | — |
rs10514919 | G/T | 0.23 | 0.29 | .001 | 0.71 (0.58, 0.87) | — |
rs8073827 | G/T | 0.28 | 0.33 | .03 | 0.80 (0.66, 0.97) | — |
rs3851806 | G/C | 0.17 | 0.18 | .4 | 0.90 (0.70, 1.15) | — |
rs5918 | T/C | 0.13 | 0.18 | .001 | 0.66 (0.52, 0.85) | — |
rs5919 | T/C | 0.08 | 0.05 | .004 | 1.77 (1.20, 2.60) | × |
rs951351 | C/T | 0.04 | 0.04 | .8 | 1.07 (0.67, 1.71) | — |
rs2292863 | G/C | 0.27 | 0.33 | .002 | 0.73 (0.60, 0.90) | — |
rs3785872 | G/A | 0.10 | 0.11 | .5 | 0.89 (0.66, 1.22) | × |
rs3809863 | C/T | 0.48 | 0.47 | .5 | 1.06 (0.89, 1.27) | × |
Gene*, SNP . | SNP results . | |||||
---|---|---|---|---|---|---|
Alleles . | MAF patients . | MAF controls . | P . | OR† (95% CI) . | SNPs in LR‡ . | |
CREB1 | ||||||
rs2551640 | A/G | 0.37 | 0.31 | .009 | 1.30 (1.07, 1.59) | — |
rs2709359 | G/A | 0.021 | 0.037 | .03 | 0.54 (0.30, 0.95) | — |
rs2709360 | T/C | 0.022 | 0.037 | .05 | 0.57 (0.32, 1.00) | × |
rs2709402 | C/A | 0.17 | 0.22 | .004 | 0.70 (0.56, 0.89) | × |
rs10932201 | G/A | 0.47 | 0.46 | 1.0 | 1.00 (0.83, 1.20) | × |
rs2551919 | C/T | 0.17 | 0.22 | .002 | 0.69 (0.55, 0.88) | — |
rs3770704 | T/C | 0.016 | 0.009 | .2 | 1.70 (0.73, 3.94) | × |
FGG | ||||||
rs1800792 | A/G | 0.51 | 0.42 | .0002 | 1.44 (1.19, 1.73) | × |
MAP3K5 | ||||||
rs2327742 | A/G | 0.19 | 0.14 | .004 | 1.44 (1.12, 1.84) | — |
rs13203080 | G/A | 0.13 | 0.14 | .2 | 0.85 (0.64, 1.11) | — |
rs7755097 | T/C | 0.18 | 0.14 | .02 | 1.35 (1.05, 1.74) | × |
rs2327743 | T/C | 0.20 | 0.14 | .002 | 1.48 (1.16, 1.89) | — |
rs2076262 | T/C | 0.02 | 0.00 | .01 | 4.06 (1.34, 12.3) | × |
rs12164028 | A/G | 0.02 | 0.01 | .02 | 3.08 (1.23, 7.71) | × |
rs2064205 | C/T | 0.38 | 0.38 | .9 | 1.01 (0.84, 1.22) | — |
rs6906871 | A/C | 0.38 | 0.37 | .7 | 1.03 (0.86, 1.24) | — |
rs2237269 | G/C | 0.16 | 0.17 | .4 | 0.91 (0.71, 1.16) | × |
rs6904753 | C/T | 0.19 | 0.19 | 1.0 | 0.99 (0.79, 1.24) | — |
rs3765259 | C/T | 0.53 | 0.48 | .08 | 1.17 (0.98, 1.39) | × |
rs9402839 | G/A | 0.10 | 0.11 | .5 | 0.89 (0.65, 1.22) | — |
rs4363056 | T/C | 0.42 | 0.38 | .09 | 1.18 (0.98, 1.42) | — |
rs7753357 | T/A | 0.07 | 0.09 | .05 | 0.71 (0.51, 1.00) | — |
rs7748892 | A/G | 0.04 | 0.04 | 1.0 | 1.01 (0.63, 1.62) | × |
rs6570087 | C/A | 0.03 | 0.04 | .3 | 0.74 (0.42, 1.27) | × |
rs10484491 | A/G | 0.49 | 0.46 | .3 | 1.10 (0.91, 1.32) | × |
rs4896219 | A/C | 0.48 | 0.48 | .9 | 1.02 (0.85, 1.22) | × |
rs932589 | G/A | 0.40 | 0.41 | .6 | 0.95 (0.78, 1.15) | × |
rs9402845 | G/A | 0.38 | 0.39 | .9 | 0.98 (0.82, 1.18) | × |
rs1570054 | C/T | 0.36 | 0.38 | .4 | 0.91 (0.75, 1.11) | × |
RIPK3 | ||||||
rs3212254 | C/A | 0.04 | 0.07 | .004 | 0.55 (0.37, 0.82) | × |
rs724165 | A/G | 0.40 | 0.44 | 0.1 | 0.87 (0.72, 1.05) | × |
rs3212247 | T/C | 0.06 | 0.08 | 0.1 | 0.75 (0.52, 1.07) | — |
rs3212243 | A/G | 0.28 | 0.24 | 0.07 | 1.22 (0.99, 1.50) | × |
LSP1 | ||||||
rs2089910 | C/T | 0.26 | 0.19 | .0005 | 1.49 (1.19, 1.86) | × |
rs3817197 | G/A | 0.50 | 0.47 | 0.2 | 1.13 (0.93, 1.36) | × |
TRAF1 | ||||||
rs4836834 | A/T | 0.45 | 0.41 | .03 | 1.22 (1.02, 1.47) | × |
rs2269059 | T/A | 0.11 | 0.065 | .0007 | 1.78 (1.28, 2.48) | × |
rs1930781 | A/G | 0.34 | 0.34 | .8 | 1.02 (0.84, 1.24) | — |
rs3761846 | T/C | 0.45 | 0.40 | .02 | 1.24 (1.03, 1.50) | — |
rs2416806 | C/G | 0.34 | 0.33 | .8 | 1.03 (0.85, 1.25) | — |
DUSP2 | ||||||
rs1724120 | G/A | 0.37 | 0.44 | .001 | 0.74 (0.61, 0.89) | × |
ITGB3 | ||||||
rs2317385 | C/T | 0.16 | 0.18 | .6 | 0.93 (0.73, 1.19) | — |
rs2056131 | C/T | 0.34 | 0.30 | .1 | 1.17 (0.96, 1.42) | × |
rs4525555 | C/T | 0.31 | 0.34 | .1 | 0.87 (0.72, 1.05) | — |
rs10514919 | G/T | 0.23 | 0.29 | .001 | 0.71 (0.58, 0.87) | — |
rs8073827 | G/T | 0.28 | 0.33 | .03 | 0.80 (0.66, 0.97) | — |
rs3851806 | G/C | 0.17 | 0.18 | .4 | 0.90 (0.70, 1.15) | — |
rs5918 | T/C | 0.13 | 0.18 | .001 | 0.66 (0.52, 0.85) | — |
rs5919 | T/C | 0.08 | 0.05 | .004 | 1.77 (1.20, 2.60) | × |
rs951351 | C/T | 0.04 | 0.04 | .8 | 1.07 (0.67, 1.71) | — |
rs2292863 | G/C | 0.27 | 0.33 | .002 | 0.73 (0.60, 0.90) | — |
rs3785872 | G/A | 0.10 | 0.11 | .5 | 0.89 (0.66, 1.22) | × |
rs3809863 | C/T | 0.48 | 0.47 | .5 | 1.06 (0.89, 1.27) | × |