Association between donor chimerism and leukocyte enzymes levels and cell source (at latest follow-up) in patients who are “alive and engrafted”
. | MSD (%) . | MUD (%) . | TCD-MUD (%) . | UCB (%) . | P value . |
---|---|---|---|---|---|
Chimerism | n = 30 | n = 35 | n = 19 | n = 79 | |
Full (>95%) | 21 (70) | 26 (74) | 9 (50) | 69 (93) | .039 |
Mixed (50-95%) | 6 | 6 | 4 | 5 | |
Mixed (10-50%) | 3 | 3 | 5 | 0 | |
Missing | 0 | 0 | 1 | 5 | |
Enzyme level* | |||||
Normal | 16 (54) | 23 (66) | 5 (53) | 64 (98) | .007 |
Low | 10 | 12 | 4 | 1 | |
Missing | 2 | 0 | 9 | 14 |
. | MSD (%) . | MUD (%) . | TCD-MUD (%) . | UCB (%) . | P value . |
---|---|---|---|---|---|
Chimerism | n = 30 | n = 35 | n = 19 | n = 79 | |
Full (>95%) | 21 (70) | 26 (74) | 9 (50) | 69 (93) | .039 |
Mixed (50-95%) | 6 | 6 | 4 | 5 | |
Mixed (10-50%) | 3 | 3 | 5 | 0 | |
Missing | 0 | 0 | 1 | 5 | |
Enzyme level* | |||||
Normal | 16 (54) | 23 (66) | 5 (53) | 64 (98) | .007 |
Low | 10 | 12 | 4 | 1 | |
Missing | 2 | 0 | 9 | 14 |
Within the MSD group, part of the donors will be carriers, which is biologically associated with lower enzymes.
Enzyme levels according to institutional references.