Relationship among stem cell source, chimerism, and post-HCT enzyme levels
| . | Matched sibling, n (%) . | Matched unrelated, n (%) . | T-cell–depleted unrelated, n (%) . | Unrelated cord blood, n (%) . |
|---|---|---|---|---|
| Chimerism | ||||
| Full (>95%) | 21 (70%) | 26 (74%) | 9 (50%) | 69 (93%) |
| Mixed (50%-95%) | 6 (20%) | 6 (17%) | 4 (22%) | 5 (7%) |
| Mixed (10%-50%) | 3 (10%) | 3 (9%) | 5 (28%) | 0 |
| Missing | 0 | 0 | 1 | 5 |
| Enzyme level | ||||
| Normal | 16 (62%) | 23 (66%) | 5 (56%) | 64 (98%) |
| Low | 10 (38%) | 12 (34%) | 4 (44%) | 1 (2%) |
| Missing | 2 | 0 | 9 | 14 |
| . | Matched sibling, n (%) . | Matched unrelated, n (%) . | T-cell–depleted unrelated, n (%) . | Unrelated cord blood, n (%) . |
|---|---|---|---|---|
| Chimerism | ||||
| Full (>95%) | 21 (70%) | 26 (74%) | 9 (50%) | 69 (93%) |
| Mixed (50%-95%) | 6 (20%) | 6 (17%) | 4 (22%) | 5 (7%) |
| Mixed (10%-50%) | 3 (10%) | 3 (9%) | 5 (28%) | 0 |
| Missing | 0 | 0 | 1 | 5 |
| Enzyme level | ||||
| Normal | 16 (62%) | 23 (66%) | 5 (56%) | 64 (98%) |
| Low | 10 (38%) | 12 (34%) | 4 (44%) | 1 (2%) |
| Missing | 2 | 0 | 9 | 14 |
Outcomes of transplantation using various hematopoietic cell sources in children with Hurler syndrome after myeloablative conditioning. Adapted from Boelens et al that begins on page 3981.