Suggested thresholds defining failure, suboptimal response, and optimal response.
. | 3 Months . | 6 Months . | 12 Months . | 18 Months . |
---|---|---|---|---|
Failure | No hematologic response | > 95% Ph+ | > 35% Ph+ | > 0% Ph+ |
Suboptimal Response | No complete hematologic response | 35–95% Ph+ | 1–35% Ph+ | 0% Ph+, < 3 log ⇓ in BCR-ABL transcripts |
Optimal response | 1–2 log ⇓ in BCR-ABL transcripts | < 35% Ph+ | 0% Ph+, ≥ 3 log ⇓ in BCR-ABL transcripts | 0% Ph+, ≥ 3 log ⇓ in BCR-ABL transcripts |
. | 3 Months . | 6 Months . | 12 Months . | 18 Months . |
---|---|---|---|---|
Failure | No hematologic response | > 95% Ph+ | > 35% Ph+ | > 0% Ph+ |
Suboptimal Response | No complete hematologic response | 35–95% Ph+ | 1–35% Ph+ | 0% Ph+, < 3 log ⇓ in BCR-ABL transcripts |
Optimal response | 1–2 log ⇓ in BCR-ABL transcripts | < 35% Ph+ | 0% Ph+, ≥ 3 log ⇓ in BCR-ABL transcripts | 0% Ph+, ≥ 3 log ⇓ in BCR-ABL transcripts |