Table 3. CD8 T M cell yield, purity, and... | American Society of Hematology

Table 3.

CD8⁺ T_M cell yield, purity, and infusion dose after tandem selection

Dose level	Cell count, × 10⁹						Recovery of CD8⁺CD45RA^– cells after tandem selection, %		CD8⁺CD45RA^– cells in infused product, %		Infused product cell count, × 10⁶ per kg
	Before CD8⁺ CD45RA^– selection		After CD45RA reduction		After CD8 enrichment		Recovery of CD8⁺CD45RA^– cells after tandem selection, %		CD8⁺CD45RA^– cells in infused product, %		Infused product cell count, × 10⁶ per kg
	Mean	Range	Mean	Range	Mean	Range	Mean	Range	Mean	Range	Mean	Range
1	1.3	0.9-1.6	0.7	0.6-0.9	0.4	0.2-0.9	30.7	12.5-54.1	85.7	80.1-96.8	1.0	1.0-1.0
2	3.3	2.4-4.3	3.0	1.2-4.6	1.18	0.5-1.9	38.8	34.6-44.3	97.5	96.4-99.7	5.0	5.0-5.0
3	3.3	0.9-7.8	2.8	0.9-6.9	1.2	0.4-3.1	39.6	27.7-61.5	93.1	80.5-98.6	8.7	5.2-10.0

Dose level	Cell count, × 10⁹						Recovery of CD8⁺CD45RA^– cells after tandem selection, %		CD8⁺CD45RA^– cells in infused product, %		Infused product cell count, × 10⁶ per kg
	Before CD8⁺ CD45RA^– selection		After CD45RA reduction		After CD8 enrichment		Recovery of CD8⁺CD45RA^– cells after tandem selection, %		CD8⁺CD45RA^– cells in infused product, %		Infused product cell count, × 10⁶ per kg
	Mean	Range	Mean	Range	Mean	Range	Mean	Range	Mean	Range	Mean	Range
1	1.3	0.9-1.6	0.7	0.6-0.9	0.4	0.2-0.9	30.7	12.5-54.1	85.7	80.1-96.8	1.0	1.0-1.0
2	3.3	2.4-4.3	3.0	1.2-4.6	1.18	0.5-1.9	38.8	34.6-44.3	97.5	96.4-99.7	5.0	5.0-5.0
3	3.3	0.9-7.8	2.8	0.9-6.9	1.2	0.4-3.1	39.6	27.7-61.5	93.1	80.5-98.6	8.7	5.2-10.0