Multivariable regression models for association between nonpermissive DPB1 mismatches and clinical outcome
| . | TCE-X nonpermissive (n = 1166) . | TCE-FD nonpermissive (n = 1279) . | ||
|---|---|---|---|---|
| HR (95% CI) . | P . | HR (95% CI) . | P . | |
| OS | 1.15 (1.04-1.27) | .005 | 1.12 (1.01-1.23) | .028 |
| DFS | 1.11 (1.00-1.22) | .044 | 1.07 (0.97-1.18) | .159 |
| TRM | 1.231 (1.14-1.50) | <.001 | 1.26 (1.1-1.44) | <.001 |
| Relapse | 0.93 (0.81-1.07) | .307 | 0.91 (0.79-1.05) | .194 |
| cGVHD | 1.20 (1.07-1.34) | .002 | 1.22 (1.09-1.36) | <.001 |
| aGVHD II-IV | 1.16 (1.03-1.30) | .014 | 1.22 (1.09-1.37) | <.001 |
| aGVHD III-IV | 1.08 (0.90-1.29) | .428 | 1.03 (0.86-1.24) | .759 |
| . | TCE-X nonpermissive (n = 1166) . | TCE-FD nonpermissive (n = 1279) . | ||
|---|---|---|---|---|
| HR (95% CI) . | P . | HR (95% CI) . | P . | |
| OS | 1.15 (1.04-1.27) | .005 | 1.12 (1.01-1.23) | .028 |
| DFS | 1.11 (1.00-1.22) | .044 | 1.07 (0.97-1.18) | .159 |
| TRM | 1.231 (1.14-1.50) | <.001 | 1.26 (1.1-1.44) | <.001 |
| Relapse | 0.93 (0.81-1.07) | .307 | 0.91 (0.79-1.05) | .194 |
| cGVHD | 1.20 (1.07-1.34) | .002 | 1.22 (1.09-1.36) | <.001 |
| aGVHD II-IV | 1.16 (1.03-1.30) | .014 | 1.22 (1.09-1.37) | <.001 |
| aGVHD III-IV | 1.08 (0.90-1.29) | .428 | 1.03 (0.86-1.24) | .759 |
Data are shown using permissive mismatches as reference (n = 1564 for TCE-X and n = 1451 for TCE-FD).