Patient characteristics of the women included in the cohort
| . | LoVIC . |
|---|---|
| Diagnosis, n | |
| Low VWF | 120 |
| Age, median (range), y | |
| At diagnosis | 33 (14.0-66.0) |
| At enrollment | 38.4 (18.0-72.0) |
| Blood group, n (%) | |
| O | 107 (89.2) |
| A | 10 (8.3) |
| B | 2 (1.6) |
| AB | 1 (0.8) |
| Plasma VWF levels, median (range), IU/dL | |
| Enrollment levels | |
| VWF:Ag | 59 (36-116) |
| VWF:RCo | 46 (30-108) |
| VWF:CB | 49 (30-100) |
| FVIII:C | 75 (36-75) |
| Lowest levels | |
| VWF:Ag | 49 (33-72) |
| VWF:RCo | 39 (30-54) |
| VWF:CB | 42 (30-91) |
| FVIII:C | 69 (29-128) |
| VWF:RCo/VWF:Ag | 0.79 (0.51-1.13) |
| VWF:CB/VWF:Ag | 0.84 (0.57-1.34) |
| Bleeding scores | |
| ISTH BAT score | |
| Median score (range) | 8 (0-24) |
| Positive score ≥6, n (%) | 95 (79.2) |
| Condensed MCMDM-1 VWD score | |
| Median score (range) | 5 (−2 to 18) |
| Positive score ≥4, n ( %) | 88 (73.3) |
| . | LoVIC . |
|---|---|
| Diagnosis, n | |
| Low VWF | 120 |
| Age, median (range), y | |
| At diagnosis | 33 (14.0-66.0) |
| At enrollment | 38.4 (18.0-72.0) |
| Blood group, n (%) | |
| O | 107 (89.2) |
| A | 10 (8.3) |
| B | 2 (1.6) |
| AB | 1 (0.8) |
| Plasma VWF levels, median (range), IU/dL | |
| Enrollment levels | |
| VWF:Ag | 59 (36-116) |
| VWF:RCo | 46 (30-108) |
| VWF:CB | 49 (30-100) |
| FVIII:C | 75 (36-75) |
| Lowest levels | |
| VWF:Ag | 49 (33-72) |
| VWF:RCo | 39 (30-54) |
| VWF:CB | 42 (30-91) |
| FVIII:C | 69 (29-128) |
| VWF:RCo/VWF:Ag | 0.79 (0.51-1.13) |
| VWF:CB/VWF:Ag | 0.84 (0.57-1.34) |
| Bleeding scores | |
| ISTH BAT score | |
| Median score (range) | 8 (0-24) |
| Positive score ≥6, n (%) | 95 (79.2) |
| Condensed MCMDM-1 VWD score | |
| Median score (range) | 5 (−2 to 18) |
| Positive score ≥4, n ( %) | 88 (73.3) |