Table 3.
Cytotoxicity of IMGN632, X-ADC, and GO in normal bone marrow samples
Sample no.
.
IMGN632 IC
90
, pM
.
X-ADC IC
90
, pM
.
GO IC
90
, pM
.
1
3500
NT
770
2
5700
NT
10 000
3
910
NT
>10 000
4
210
NT
3 600
5
1000
45
>10 000
6
1900
60
>10 000
7
290
26
>10 000
8
3700
66
760
9
180
14
2 700
10
3500
77
10 000
11
3500
37
>10 000
Sample no.
.
IMGN632 IC
90
, pM
.
X-ADC IC
90
, pM
.
GO IC
90
, pM
.
1
3500
NT
770
2
5700
NT
10 000
3
910
NT
>10 000
4
210
NT
3 600
5
1000
45
>10 000
6
1900
60
>10 000
7
290
26
>10 000
8
3700
66
760
9
180
14
2 700
10
3500
77
10 000
11
3500
37
>10 000
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