Univariate and multivariate analysis of variables affecting PFS
| Variable . | Univariate analysis . | Multivariate analysis . | ||||
|---|---|---|---|---|---|---|
| HR . | 95% CI . | P . | HR . | 95% CI . | P . | |
| Age, ≥70 y | 1.68 | 1.12-2.52 | .011 | 1.85 | 1.21-2.83 | .004 |
| Male sex | 1.11 | 0.76-1.62 | .591 | — | — | — |
| Creatinine level >2.0 mg/dL | 1.70 | 1.09-2.65 | .02 | 1.50 | 0.91-2.50 | .12 |
| D-S stage 3 | 1.49 | 0.97-2.29 | .072 | — | — | — |
| R-ISS 3 | 1.50 | 1.00-2.26 | .05 | 1.44 | 0.917-2.24 | .11 |
| % of BM CD138+ cells | 1.00 | 1.00-1.01 | .565 | — | — | — |
| HDT + ASCT | 0.70 | 0.45-1.08 | .11 | — | — | — |
| MDCT pattern | ||||||
| Fatty | 1 (reference) | 1 (reference) | ||||
| Focal/scattered | 1.53 | 0.99 | .056 | 1.53 | 0.96-2.43 | .08 |
| Diffuse | 2.09 | 1.25-3.49 | .005 | 1.92 | 1.12-3.31 | .018 |
| Variable . | Univariate analysis . | Multivariate analysis . | ||||
|---|---|---|---|---|---|---|
| HR . | 95% CI . | P . | HR . | 95% CI . | P . | |
| Age, ≥70 y | 1.68 | 1.12-2.52 | .011 | 1.85 | 1.21-2.83 | .004 |
| Male sex | 1.11 | 0.76-1.62 | .591 | — | — | — |
| Creatinine level >2.0 mg/dL | 1.70 | 1.09-2.65 | .02 | 1.50 | 0.91-2.50 | .12 |
| D-S stage 3 | 1.49 | 0.97-2.29 | .072 | — | — | — |
| R-ISS 3 | 1.50 | 1.00-2.26 | .05 | 1.44 | 0.917-2.24 | .11 |
| % of BM CD138+ cells | 1.00 | 1.00-1.01 | .565 | — | — | — |
| HDT + ASCT | 0.70 | 0.45-1.08 | .11 | — | — | — |
| MDCT pattern | ||||||
| Fatty | 1 (reference) | 1 (reference) | ||||
| Focal/scattered | 1.53 | 0.99 | .056 | 1.53 | 0.96-2.43 | .08 |
| Diffuse | 2.09 | 1.25-3.49 | .005 | 1.92 | 1.12-3.31 | .018 |
—, not calculated; HR, hazard ratio. Other abbreviations are explained in Table 1.