Multivariable associations of patient and treatment characteristics with OS and LSS among AYA with ALL, ages 15-39 y, 2004-2014, California
| . | OS . | LSS . | ||
|---|---|---|---|---|
| . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Sex | .27 | .64 | ||
| Female | 0.91 (0.76-1.08) | 0.96 (0.79-1.16) | ||
| Male | Ref. | Ref. | ||
| Age at diagnosis, y | .07 | .38 | ||
| 15-18 | 0.75 (0.51-1.10) | 0.86 (0.58-1.29) | ||
| 19-24 | 0.83 (0.63-1.08) | 0.85 (0.64-1.14) | ||
| 25-29 | 1.13 (0.84-1.51) | 1.08 (0.79-1.49) | ||
| 30-34 | 1.08 (0.81-1.44) | 1.09 (0.80-1.48) | ||
| 35-39 | Ref. | Ref. | ||
| Race/ethnicity | <.001 | <.001 | ||
| Asian/PI | 1.1 (0.79-1.08) | 1.14 (0.76-1.71) | ||
| Hispanic | 1.64 (1.30-2.06) | 1.76 (1.39-2.24) | ||
| NH African American | 2.07 (1.28-3.35) | 2.01 (1.19-3.39) | ||
| Other/ unknown | 1.97 (0.72-5.40) | 2.41 (0.88-6.61) | ||
| NH white | Ref. | Ref. | ||
| Treatment setting | .001 | <.001 | ||
| Pediatric | 0.53 (0.37-0.76) | 0.51 (0.35-0.74) | ||
| Adult | Ref. | Ref. | ||
| Induction facility is COG center or NCI CC | .019 | .026 | ||
| Yes | 0.80 (0.66-0.96) | 0.80 (0.65-0.97) | ||
| No | Ref. | Ref. | ||
| . | OS . | LSS . | ||
|---|---|---|---|---|
| . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Sex | .27 | .64 | ||
| Female | 0.91 (0.76-1.08) | 0.96 (0.79-1.16) | ||
| Male | Ref. | Ref. | ||
| Age at diagnosis, y | .07 | .38 | ||
| 15-18 | 0.75 (0.51-1.10) | 0.86 (0.58-1.29) | ||
| 19-24 | 0.83 (0.63-1.08) | 0.85 (0.64-1.14) | ||
| 25-29 | 1.13 (0.84-1.51) | 1.08 (0.79-1.49) | ||
| 30-34 | 1.08 (0.81-1.44) | 1.09 (0.80-1.48) | ||
| 35-39 | Ref. | Ref. | ||
| Race/ethnicity | <.001 | <.001 | ||
| Asian/PI | 1.1 (0.79-1.08) | 1.14 (0.76-1.71) | ||
| Hispanic | 1.64 (1.30-2.06) | 1.76 (1.39-2.24) | ||
| NH African American | 2.07 (1.28-3.35) | 2.01 (1.19-3.39) | ||
| Other/ unknown | 1.97 (0.72-5.40) | 2.41 (0.88-6.61) | ||
| NH white | Ref. | Ref. | ||
| Treatment setting | .001 | <.001 | ||
| Pediatric | 0.53 (0.37-0.76) | 0.51 (0.35-0.74) | ||
| Adult | Ref. | Ref. | ||
| Induction facility is COG center or NCI CC | .019 | .026 | ||
| Yes | 0.80 (0.66-0.96) | 0.80 (0.65-0.97) | ||
| No | Ref. | Ref. | ||
Final model includes age, sex, and all variables significant at the P < .10 level.
Ref, reference.