CNVs seen in UCD and HHV8−/iMCD and FDSCs arising from UCD
| Genes . | Cases . | CNV type . | CNV exons . | CNV ratio . |
|---|---|---|---|---|
| UCD and MCD | ||||
| ETS1 | 3, 5 | Gain | 10 of 10 | 1.43 |
| PTPN6 | 3, 5 | Gain | 16 of 17 | 1.39 |
| TGFBR2 | 3, 5 | Gain | 8 of 8 | 1.45 |
| TUSC3 | 3 | Gain | 9 of 11 | 1.4 |
| IKZF3 | 5 | Gain | 8 of 9 | 1.47 |
| PIM1 | 5 | Gain | 7 of 7 | 1.42 |
| HIST genes | 14 | Gain | 1 of 1 | 1.35-1.93 |
| FDCSs | ||||
| BRAF | 19, 20 | Deletion | 5 of 18; 8 of 18 | −1.15 |
| FANCB | 19 | Deletion | 3 of 10 | −1.17 |
| FANCB | 20 | Gain | 6 of 10 | 0.67 |
| JAK2 | 19, 20 | Deletion | 4 of 25, 6 of 25 | −1.15, −1.02 |
| MAP3K5 | 19 | Gain | 3 of 30 | 1.22 |
| MSH3 | 19 | Deletion | 2 of 24 | −1.71 |
| NFKB1 | 19 | Deletion | 4 of 24 | −1.59 |
| AR | 20 | Gain | 8 of 8 | 1.2 |
| HIST1H1D | 20 | Deletion | 1 of 1 | −0.69 |
| HIST1H3A | 20 | Deletion | 1 of 1 | −0.68 |
| HIST1H3E | 20 | Deletion | 1 of 1 | −0.68 |
| MAP3K15 | 20 | Gain | 29 of 29 | 0.94 |
| MED12 | 20 | Gain | 45 of 45 | 0.81 |
| NPM1 | 20 | Deletion | 2 of 10 | −0.75 |
| VCAM1 | 21 | Gain | 5 of 9 | 0.86 |
| Genes . | Cases . | CNV type . | CNV exons . | CNV ratio . |
|---|---|---|---|---|
| UCD and MCD | ||||
| ETS1 | 3, 5 | Gain | 10 of 10 | 1.43 |
| PTPN6 | 3, 5 | Gain | 16 of 17 | 1.39 |
| TGFBR2 | 3, 5 | Gain | 8 of 8 | 1.45 |
| TUSC3 | 3 | Gain | 9 of 11 | 1.4 |
| IKZF3 | 5 | Gain | 8 of 9 | 1.47 |
| PIM1 | 5 | Gain | 7 of 7 | 1.42 |
| HIST genes | 14 | Gain | 1 of 1 | 1.35-1.93 |
| FDCSs | ||||
| BRAF | 19, 20 | Deletion | 5 of 18; 8 of 18 | −1.15 |
| FANCB | 19 | Deletion | 3 of 10 | −1.17 |
| FANCB | 20 | Gain | 6 of 10 | 0.67 |
| JAK2 | 19, 20 | Deletion | 4 of 25, 6 of 25 | −1.15, −1.02 |
| MAP3K5 | 19 | Gain | 3 of 30 | 1.22 |
| MSH3 | 19 | Deletion | 2 of 24 | −1.71 |
| NFKB1 | 19 | Deletion | 4 of 24 | −1.59 |
| AR | 20 | Gain | 8 of 8 | 1.2 |
| HIST1H1D | 20 | Deletion | 1 of 1 | −0.69 |
| HIST1H3A | 20 | Deletion | 1 of 1 | −0.68 |
| HIST1H3E | 20 | Deletion | 1 of 1 | −0.68 |
| MAP3K15 | 20 | Gain | 29 of 29 | 0.94 |
| MED12 | 20 | Gain | 45 of 45 | 0.81 |
| NPM1 | 20 | Deletion | 2 of 10 | −0.75 |
| VCAM1 | 21 | Gain | 5 of 9 | 0.86 |