Karyotypes of the pre–B-cell cALL relapse patients
| Patient ID . | Karyotype (PT) . | Karyotype (R events) . |
|---|---|---|
| 34 | 46,XY | 46,XY |
| 62 | 54,XY,+4,+6,+8,+10,+14,+17,+18,+21 | 55,XXY,+4,+6,+8,+10,+14,+der(17)del(17)(p12),+18,+21[12]/46,XY[7] |
| 64 | 46,XX | 46,XX,t(7;11)(q32;q14),+der(11)t(1;7;11)(q21;q32;q14),-21[17]/46,XX,idem,t(9;22)(p24;q22.1)[8] |
| 217 | 46,XX,inv(4)(p14q27),del(9)(p22) | 46,XX,inv(4)(p14q28),del(9)(p22),t(12;14)(q12;q11)[8]/46,XX,inv(4)(p14q28),del(9)(p22)[3] |
| 325* | 46,XY | NA|NA|NA|NA |
| 382 | 47,XY,t(9;14)(p13;q32),+mar | NA | 47,XY,del(2)(p22?),add(3)(p25),t(9;14)(p13;q32),t(16;Y)(q24;q11.2),+mar |
| 391 | 52,XY,+3,+6,+11,+17,+21,+22 | 52,XY,+X,+6,+14,+17,+21,+21 |
| 394 | 46,XX,-12,-21,+mar1,+mar2 | 46,XX,-12,-21,+mar1,+mar2[1]/46,XX,der(12),-21,+mar3[5] |
| 445 | NA | 47∼48,-X,der(1),del(1)x2,-6,der(8),der(17),+21,+21,+mar | NA |
| 447 | 47,XX,add(6)(q27),der(15)t(?13;15)(p11;p11),add(20)(?q11.2),+21 | 47,XX,add(1)(q32),add(6)(q27),der(15)(p11),+21 |
| 579* | 46,XY | 46,XY | 46,XY |
| 659 | 55,XXY,+2,+?3,+4,+6,+10,+14,+18,+21 | 54,XY,+4,+6,del(9)(p21),+10,del(12)(p13),+17,+21 |
| 670 | 51∼56,XY,+X,+2,+4,+6,+9,+10,+14,+17,+21 | 53,XY,+4,+6,+8,+10,+14,+17,+21 |
| 684* | 46,XX | 46,XX | 46,XX,dup(1)(q21q23) |
| 717 | 46,XX,hsr(21)(q22.1) | 46,XX,hsr(21)(q22.1) |
| 764 | 56,XY,+X,+4,+5,+6,del(9p),+10,+14,+17,+18,+21,+21 | NA |
| 772* | 23∼39,X,Y,+3,+5,+14,+16,+17,+20,[9]/52,XY,+X,+Y,+14,+20,+21,+21[13] | 26∼27,XY,+14,+18,+21 |
| 786 | NA | NA | NA |
| 808* | 46,XY,t(11;19)(q23;p13.1) | 46,XY,t(11;19)(q23;p13.1) |
| Patient ID . | Karyotype (PT) . | Karyotype (R events) . |
|---|---|---|
| 34 | 46,XY | 46,XY |
| 62 | 54,XY,+4,+6,+8,+10,+14,+17,+18,+21 | 55,XXY,+4,+6,+8,+10,+14,+der(17)del(17)(p12),+18,+21[12]/46,XY[7] |
| 64 | 46,XX | 46,XX,t(7;11)(q32;q14),+der(11)t(1;7;11)(q21;q32;q14),-21[17]/46,XX,idem,t(9;22)(p24;q22.1)[8] |
| 217 | 46,XX,inv(4)(p14q27),del(9)(p22) | 46,XX,inv(4)(p14q28),del(9)(p22),t(12;14)(q12;q11)[8]/46,XX,inv(4)(p14q28),del(9)(p22)[3] |
| 325* | 46,XY | NA|NA|NA|NA |
| 382 | 47,XY,t(9;14)(p13;q32),+mar | NA | 47,XY,del(2)(p22?),add(3)(p25),t(9;14)(p13;q32),t(16;Y)(q24;q11.2),+mar |
| 391 | 52,XY,+3,+6,+11,+17,+21,+22 | 52,XY,+X,+6,+14,+17,+21,+21 |
| 394 | 46,XX,-12,-21,+mar1,+mar2 | 46,XX,-12,-21,+mar1,+mar2[1]/46,XX,der(12),-21,+mar3[5] |
| 445 | NA | 47∼48,-X,der(1),del(1)x2,-6,der(8),der(17),+21,+21,+mar | NA |
| 447 | 47,XX,add(6)(q27),der(15)t(?13;15)(p11;p11),add(20)(?q11.2),+21 | 47,XX,add(1)(q32),add(6)(q27),der(15)(p11),+21 |
| 579* | 46,XY | 46,XY | 46,XY |
| 659 | 55,XXY,+2,+?3,+4,+6,+10,+14,+18,+21 | 54,XY,+4,+6,del(9)(p21),+10,del(12)(p13),+17,+21 |
| 670 | 51∼56,XY,+X,+2,+4,+6,+9,+10,+14,+17,+21 | 53,XY,+4,+6,+8,+10,+14,+17,+21 |
| 684* | 46,XX | 46,XX | 46,XX,dup(1)(q21q23) |
| 717 | 46,XX,hsr(21)(q22.1) | 46,XX,hsr(21)(q22.1) |
| 764 | 56,XY,+X,+4,+5,+6,del(9p),+10,+14,+17,+18,+21,+21 | NA |
| 772* | 23∼39,X,Y,+3,+5,+14,+16,+17,+20,[9]/52,XY,+X,+Y,+14,+20,+21,+21[13] | 26∼27,XY,+14,+18,+21 |
| 786 | NA | NA | NA |
| 808* | 46,XY,t(11;19)(q23;p13.1) | 46,XY,t(11;19)(q23;p13.1) |
Karyotypes of each relapse event per patient are separated by a vertical bar.
NA, not available.
Hypermutable cases.