Table 3.

Immune reconstitution of patients after haplo-HCT

1 mo3 mo6 mo12 mo24 mo
TCRαβ+/CD19+-depleted HCT*      
 CD3+ T cells/µL 265 ± 110 366 ± 229 707 ± 179 832 ± 250 1640 ± 414 
 CD3+CD4+ T cells/µL 33 ± 17 58 ± 23 190 ± 38 295 ± 74 608 ± 106 
 CD3+CD8+ T cells/µL 175 ± 73 97 ± 17 272 ± 33 415 ± 140 868 ± 347 
 CD19+ B cells/µL 4 ± 2 287 ± 109 270 ± 91 307 ± 103 205 ± 60 
 CD3CD56+ NK cells/µL 199 ± 49 174 ± 53 274 ± 76 182 ± 49 429 ± 141 
CD34+*selected- and/or CD3+/CD19+-depleted HCT      
 CD3+ T cells/µL 140 ± 88 626 ± 252 736 ± 216 1014 ± 238 2390 ± 559 
 CD3+CD4+ T cells/µL 17 ± 11 78 ± 29 148 ± 43 423 ± 97 934 ± 203 
 CD3+CD8+ T cells/µL 120 ± 77 531 ± 218 528 ± 147 559 ± 147 1314 ± 311 
 CD19+ B cells/µL 9 ± 2 320 ± 94 151 ± 54 600 ± 241 539 ± 169 
 CD3CD56+ NK cells/µL 255 ± 51 152 ± 39 127 ± 27 413 ± 151 481 ± 246 
1 mo3 mo6 mo12 mo24 mo
TCRαβ+/CD19+-depleted HCT*      
 CD3+ T cells/µL 265 ± 110 366 ± 229 707 ± 179 832 ± 250 1640 ± 414 
 CD3+CD4+ T cells/µL 33 ± 17 58 ± 23 190 ± 38 295 ± 74 608 ± 106 
 CD3+CD8+ T cells/µL 175 ± 73 97 ± 17 272 ± 33 415 ± 140 868 ± 347 
 CD19+ B cells/µL 4 ± 2 287 ± 109 270 ± 91 307 ± 103 205 ± 60 
 CD3CD56+ NK cells/µL 199 ± 49 174 ± 53 274 ± 76 182 ± 49 429 ± 141 
CD34+*selected- and/or CD3+/CD19+-depleted HCT      
 CD3+ T cells/µL 140 ± 88 626 ± 252 736 ± 216 1014 ± 238 2390 ± 559 
 CD3+CD4+ T cells/µL 17 ± 11 78 ± 29 148 ± 43 423 ± 97 934 ± 203 
 CD3+CD8+ T cells/µL 120 ± 77 531 ± 218 528 ± 147 559 ± 147 1314 ± 311 
 CD19+ B cells/µL 9 ± 2 320 ± 94 151 ± 54 600 ± 241 539 ± 169 
 CD3CD56+ NK cells/µL 255 ± 51 152 ± 39 127 ± 27 413 ± 151 481 ± 246 

Data are expressed as means ± standard error of the mean.

*

There was no statistically significant difference between the 2 groups with respect to each cell subset determined at different time points.

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