Top reduced downstream functions in normal LCs
| Functions annotation . | P, -log . | Activation z-score . |
|---|---|---|
| Mitogenesis | 4.656 | −3.692 |
| Proliferation of vascular endothelial cells | 7.526 | −2.976 |
| Cell movement of tumor cell lines | 15.38 | −2.748 |
| Cell cycle progression | 4.298 | −2.703 |
| Tubulation of cells | 9.312 | −2.481 |
| Mitogenesis of endothelial cells | 4.810 | −2.330 |
| Tubulation of endothelial cell lines | 3.462 | −2.153 |
| Outgrowth of cells | 3.202 | −2.016 |
| Apoptosis | 14.33 | −2.01 |
| Tubulation of endothelial colony-forming cells | 3.013 | −2.000 |
| Functions annotation . | P, -log . | Activation z-score . |
|---|---|---|
| Mitogenesis | 4.656 | −3.692 |
| Proliferation of vascular endothelial cells | 7.526 | −2.976 |
| Cell movement of tumor cell lines | 15.38 | −2.748 |
| Cell cycle progression | 4.298 | −2.703 |
| Tubulation of cells | 9.312 | −2.481 |
| Mitogenesis of endothelial cells | 4.810 | −2.330 |
| Tubulation of endothelial cell lines | 3.462 | −2.153 |
| Outgrowth of cells | 3.202 | −2.016 |
| Apoptosis | 14.33 | −2.01 |
| Tubulation of endothelial colony-forming cells | 3.013 | −2.000 |
IPA of LC-SVEC gene signature for top-reduced downstream functions in normal LCs compared with SVECs. P value (displayed as -log) indicates the significance of an association with the change of a related function. z-score predicts the direction of the change. Negative z-score indicates a decrease of a function in LCs compared with SVECs.