Presence of MDEs at any time >30 days after receiving the diagnosis of MM
| Clinical MDE . | MM-Only (n = 20 839) . | MM+Psychiatric (n = 15 168) . | MM-Only (n = 20 839) . | MM+Depression (n = 8421) . | Preexisting psych. diagnosis (n = 9355) . | Psych. diagnosis after MM (n = 5813) . | Preexisting depression diagnosis (n = 4546) . | Depression diagnosis after MM (n = 3875) . |
|---|---|---|---|---|---|---|---|---|
| Hypercalcemia | 2 851 (13.7) | 3 487 (23.0)* | 2 851 (13.7) | 1967 (23.4)* | 2083 (22.3) | 1404 (24.2)* | 1002 (22.0) | 965 (24.9)* |
| Renal dysfunction | 4 580 (22.0) | 4 851 (32.0)* | 4 580 (22.0) | 2772 (32.9)* | 2943 (31.5) | 1908 (32.8)* | 1417 (31.2) | 1355 (35.0)* |
| Anemia | 5 626 (27.0) | 6 456 (42.6)* | 5 626 (27.0) | 3776 (44.8)* | 3984 (42.6) | 2472 (42.5) | 1941 (42.7) | 1835 (47.4)* |
| Bone fractures | 4 928 (23.6) | 5 449 (35.9)* | 4 928 (23.6) | 3230 (38.4)* | 3108 (33.2) | 2341 (40.3)* | 1564 (34.4) | 1666 (43.0)* |
| Renal dialysis | 468 (2.2) | 587 (3.9)* | 468 (2.2) | 346 (4.1)* | 345 (3.7) | 242 (4.2)* | 186 (4.1) | 160 (4.1) |
| Clinical MDE . | MM-Only (n = 20 839) . | MM+Psychiatric (n = 15 168) . | MM-Only (n = 20 839) . | MM+Depression (n = 8421) . | Preexisting psych. diagnosis (n = 9355) . | Psych. diagnosis after MM (n = 5813) . | Preexisting depression diagnosis (n = 4546) . | Depression diagnosis after MM (n = 3875) . |
|---|---|---|---|---|---|---|---|---|
| Hypercalcemia | 2 851 (13.7) | 3 487 (23.0)* | 2 851 (13.7) | 1967 (23.4)* | 2083 (22.3) | 1404 (24.2)* | 1002 (22.0) | 965 (24.9)* |
| Renal dysfunction | 4 580 (22.0) | 4 851 (32.0)* | 4 580 (22.0) | 2772 (32.9)* | 2943 (31.5) | 1908 (32.8)* | 1417 (31.2) | 1355 (35.0)* |
| Anemia | 5 626 (27.0) | 6 456 (42.6)* | 5 626 (27.0) | 3776 (44.8)* | 3984 (42.6) | 2472 (42.5) | 1941 (42.7) | 1835 (47.4)* |
| Bone fractures | 4 928 (23.6) | 5 449 (35.9)* | 4 928 (23.6) | 3230 (38.4)* | 3108 (33.2) | 2341 (40.3)* | 1564 (34.4) | 1666 (43.0)* |
| Renal dialysis | 468 (2.2) | 587 (3.9)* | 468 (2.2) | 346 (4.1)* | 345 (3.7) | 242 (4.2)* | 186 (4.1) | 160 (4.1) |