Incidence of AL amyloidosis in years 2008 to 2011
. | . | No. of cases per million person-years (numerator/denominator*) . | |||
---|---|---|---|---|---|
Sex . | Age, y . | 2008 . | 2009 . | 2010 . | 2011 . |
Female | 18-34 | 0.4 (1/2 328 356) | 0.0 (0/3 334 994) | 1.6 (5/3 179 448) | 0.9 (3/3 452 830) |
35-54 | 5.4 (24/4 458 641) | 6.6 (40/6 073 904) | 6.3 (37/5 867 133) | 4.6 (28/6 095 899) | |
55-64 | 20.8 (42/2 022 079) | 11.2 (31/2 756 439) | 13.5 (37/2 745 827) | 19.3 (57/2 958 448) | |
65+ | 26.7 (28/1 050 168) | 33.0 (51/1 543 818) | 20.5 (31/1 514 234) | 34.6 (62/1 792 636) | |
All female | 9.6 (95/9 859 244) | 8.9 (122/13 709 155) | 8.3 (110/13 306 642) | 10.5 (150/14 299 813) | |
Male | 18-34 | 0.9 (2/2 140 796) | 0.3 (1/3 048 029) | 0.3 (1/2 895 210) | 0.0 (0/3 172 642) |
35-54 | 5.1 (20/3 953 483) | 4.8 (26/5 404 324) | 4.0 (21/5 244 983) | 2.9 (16/5 449 578) | |
55-64 | 25.5 (46/1 801 702) | 14.5 (36/2 480 625) | 16.6 (41/2 473 344) | 19.0 (50/2 625 058) | |
65+ | 58.8 (50/849 850) | 54.5 (67/1 230 196) | 57.1 (72/1 261 151) | 55.3 (79/1 429 149) | |
All male | 13.5 (118/8 745 831) | 10.7 (130/12 163 174) | 11.4 (135/11 874 688) | 11.4 (145/12 676 427) | |
All sex | 18-34 | 0.7 (3/4 469 152) | 0.2 (1/6 383 023) | 1.0 (6/6 074 658) | 0.5 (3/6 625 472) |
35-54 | 5.2 (44/8 412 124) | 5.8 (66/11 478 228) | 5.2 (58/11 112 116) | 3.8 (44/11 545 477) | |
55-64 | 23.0 (88/3 823 781) | 12.8 (67/5 237 064) | 14.9 (78/5 219 171) | 19.2 (107/5 583 506) | |
65+ | 41.1 (78/1 900 018) | 42.5 (118/2 774 014) | 37.1 (103/2 775 385) | 43.8 (141/3 221 785) | |
All patients | 11.4 (213/18 605 075) | 9.7 (252/25 872 329) | 9.7 (245/25 181 330) | 10.9 (295/26 976 240) | |
US adult population | Age-sex adjusted†rate, no. of cases per million person-years | ||||
Female | 10.4 | 10.4 | 8.7 | 11.5 | |
Male | 15.2 | 12.5 | 12.9 | 12.5 | |
All | 12.7 | 11.4 | 10.8 | 12.0 |
. | . | No. of cases per million person-years (numerator/denominator*) . | |||
---|---|---|---|---|---|
Sex . | Age, y . | 2008 . | 2009 . | 2010 . | 2011 . |
Female | 18-34 | 0.4 (1/2 328 356) | 0.0 (0/3 334 994) | 1.6 (5/3 179 448) | 0.9 (3/3 452 830) |
35-54 | 5.4 (24/4 458 641) | 6.6 (40/6 073 904) | 6.3 (37/5 867 133) | 4.6 (28/6 095 899) | |
55-64 | 20.8 (42/2 022 079) | 11.2 (31/2 756 439) | 13.5 (37/2 745 827) | 19.3 (57/2 958 448) | |
65+ | 26.7 (28/1 050 168) | 33.0 (51/1 543 818) | 20.5 (31/1 514 234) | 34.6 (62/1 792 636) | |
All female | 9.6 (95/9 859 244) | 8.9 (122/13 709 155) | 8.3 (110/13 306 642) | 10.5 (150/14 299 813) | |
Male | 18-34 | 0.9 (2/2 140 796) | 0.3 (1/3 048 029) | 0.3 (1/2 895 210) | 0.0 (0/3 172 642) |
35-54 | 5.1 (20/3 953 483) | 4.8 (26/5 404 324) | 4.0 (21/5 244 983) | 2.9 (16/5 449 578) | |
55-64 | 25.5 (46/1 801 702) | 14.5 (36/2 480 625) | 16.6 (41/2 473 344) | 19.0 (50/2 625 058) | |
65+ | 58.8 (50/849 850) | 54.5 (67/1 230 196) | 57.1 (72/1 261 151) | 55.3 (79/1 429 149) | |
All male | 13.5 (118/8 745 831) | 10.7 (130/12 163 174) | 11.4 (135/11 874 688) | 11.4 (145/12 676 427) | |
All sex | 18-34 | 0.7 (3/4 469 152) | 0.2 (1/6 383 023) | 1.0 (6/6 074 658) | 0.5 (3/6 625 472) |
35-54 | 5.2 (44/8 412 124) | 5.8 (66/11 478 228) | 5.2 (58/11 112 116) | 3.8 (44/11 545 477) | |
55-64 | 23.0 (88/3 823 781) | 12.8 (67/5 237 064) | 14.9 (78/5 219 171) | 19.2 (107/5 583 506) | |
65+ | 41.1 (78/1 900 018) | 42.5 (118/2 774 014) | 37.1 (103/2 775 385) | 43.8 (141/3 221 785) | |
All patients | 11.4 (213/18 605 075) | 9.7 (252/25 872 329) | 9.7 (245/25 181 330) | 10.9 (295/26 976 240) | |
US adult population | Age-sex adjusted†rate, no. of cases per million person-years | ||||
Female | 10.4 | 10.4 | 8.7 | 11.5 | |
Male | 15.2 | 12.5 | 12.9 | 12.5 | |
All | 12.7 | 11.4 | 10.8 | 12.0 |