Table 3.

Comparison of ALL-PGH outcomes over the years

Baseline characteristicJanuary 2003-December 2007(N= 210; Lubaton et al2)June 2009-December 2011 (N= 173) (Coniconde-Arca et al3)January 2012-2016 (N= 311) (this study)
NCI risk group (LR/HR), % 44/56 60/40 47/53 
Protocol In-house ALL regimen Modified SIOP PODC ALL regimen 1 Modified SIOP PODC ALL regimen 2 
Modified Children’s Cancer Group HR regimen 
Outcome 1-y OS, 32% 1-y OS, 71% 1-y OS, 80% 
4-y EFS, 40% 4-y EFS, 46%: SR, 50.8%; HR, 42.2%; OS, 56%: SR, 62%; HR, 50% 
Baseline characteristicJanuary 2003-December 2007(N= 210; Lubaton et al2)June 2009-December 2011 (N= 173) (Coniconde-Arca et al3)January 2012-2016 (N= 311) (this study)
NCI risk group (LR/HR), % 44/56 60/40 47/53 
Protocol In-house ALL regimen Modified SIOP PODC ALL regimen 1 Modified SIOP PODC ALL regimen 2 
Modified Children’s Cancer Group HR regimen 
Outcome 1-y OS, 32% 1-y OS, 71% 1-y OS, 80% 
4-y EFS, 40% 4-y EFS, 46%: SR, 50.8%; HR, 42.2%; OS, 56%: SR, 62%; HR, 50% 
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