Comparison of ALL-PGH outcomes over the years
| Baseline characteristic . | January 2003-December 2007(N= 210; Lubaton et al2) . | June 2009-December 2011 (N= 173) (Coniconde-Arca et al3) . | January 2012-2016 (N= 311) (this study) . |
|---|---|---|---|
| NCI risk group (LR/HR), % | 44/56 | 60/40 | 47/53 |
| Protocol | In-house ALL regimen | Modified SIOP PODC ALL regimen 1 | Modified SIOP PODC ALL regimen 2 |
| Modified Children’s Cancer Group HR regimen | |||
| Outcome | 1-y OS, 32% | 1-y OS, 71% | 1-y OS, 80% |
| 4-y EFS, 40% | 4-y EFS, 46%: SR, 50.8%; HR, 42.2%; OS, 56%: SR, 62%; HR, 50% |
| Baseline characteristic . | January 2003-December 2007(N= 210; Lubaton et al2) . | June 2009-December 2011 (N= 173) (Coniconde-Arca et al3) . | January 2012-2016 (N= 311) (this study) . |
|---|---|---|---|
| NCI risk group (LR/HR), % | 44/56 | 60/40 | 47/53 |
| Protocol | In-house ALL regimen | Modified SIOP PODC ALL regimen 1 | Modified SIOP PODC ALL regimen 2 |
| Modified Children’s Cancer Group HR regimen | |||
| Outcome | 1-y OS, 32% | 1-y OS, 71% | 1-y OS, 80% |
| 4-y EFS, 40% | 4-y EFS, 46%: SR, 50.8%; HR, 42.2%; OS, 56%: SR, 62%; HR, 50% |