Patients with a final diagnosis of primary ITP
| . | Primary ITP (n = 269) . |
|---|---|
| Age at initial presentation, median (IQR), y | 50 (33-64) |
| Female, n (%) | 168 (62.5) |
| Follow-up from initial diagnosis, >1 visit, median (IQR), y | 7.0 (2.9-14.8) |
| Nadir platelet count, median (IQR) | 15 (4-48) |
| Number of ITP treatments received (IQR) | 3 (1-4) |
| Splenectomy, n (%) | 83 (30.9) |
| ITP disease stage at the time of registration,* n (%) | |
| Newly diagnosed (within first 3 mo) | 28 (10.4) |
| Persistent (3 to 12 mo) | 23 (8.6) |
| Chronic (>12 mo) | 122 (45.4) |
| Relapsed | 5 (1.9) |
| Refractory | 24 (8.9) |
| Remission off therapy | 52 (19.3) |
| Patients with a diagnosis other than ITP at registration | 10 (3.7) |
| Unknown | 5 (1.9) |
| Patients with refractory ITP at last follow-up, n (%) | 8 (3.0) |
| Worst bleed ever, n (%) | |
| None | 40 (14.9) |
| Grade 1 only | 77 (28.6) |
| Grade 2 | 152 (56.5) |
| . | Primary ITP (n = 269) . |
|---|---|
| Age at initial presentation, median (IQR), y | 50 (33-64) |
| Female, n (%) | 168 (62.5) |
| Follow-up from initial diagnosis, >1 visit, median (IQR), y | 7.0 (2.9-14.8) |
| Nadir platelet count, median (IQR) | 15 (4-48) |
| Number of ITP treatments received (IQR) | 3 (1-4) |
| Splenectomy, n (%) | 83 (30.9) |
| ITP disease stage at the time of registration,* n (%) | |
| Newly diagnosed (within first 3 mo) | 28 (10.4) |
| Persistent (3 to 12 mo) | 23 (8.6) |
| Chronic (>12 mo) | 122 (45.4) |
| Relapsed | 5 (1.9) |
| Refractory | 24 (8.9) |
| Remission off therapy | 52 (19.3) |
| Patients with a diagnosis other than ITP at registration | 10 (3.7) |
| Unknown | 5 (1.9) |
| Patients with refractory ITP at last follow-up, n (%) | 8 (3.0) |
| Worst bleed ever, n (%) | |
| None | 40 (14.9) |
| Grade 1 only | 77 (28.6) |
| Grade 2 | 152 (56.5) |
The ITP stages at registration were based on physician assessment because patient recall of dates of initial presentation was often unreliable. Disease stages were mutually exclusive.