Table 1.

Patients enrolled in the McMaster ITP Registry (2010-2016)

Diagnosis (at last follow-up)No. of patients
ITP 362 
 Primary ITP 269 
 Secondary ITP 93 
  Evan's syndrome 14 
  Systemic lupus erythematosus 13 
  Drug-induced ITP 
  Antiphospholipid antibody syndrome 
  Helicobacter pylori 
  Hepatitis C 
  ITP in pregnancy 
  Common variable immune deficiency 
  HIV 
  ITP following nonspecific viral illness or infection 
  Chronic lymphocytic leukemia 
  Lymphoproliferative disease 
  Other associated autoimmune conditions 15 
Nonimmune thrombocytopenia 149 
 Familial thrombocytopenia (suspected or confirmed) 35 
 Splenomegaly 27 
 Incidental thrombocytopenia of pregnancy 20 
 Myelodysplastic syndrome 20 
 Liver disease 16 
 Pseudothrombocytopenia 13 
 Alcohol-related thrombocytopenia 
 Pancytopenia 
 Thrombocytopenia associated with malignancy 
 Other 
Isolated mild thrombocytopenia (100-150 × 109/L) 67 
Other immune platelet disorders 23 
 Thrombotic microangiopathy 19 
 Cyclic thrombocytopenia 
Unknown 13 
Total 614 
Diagnosis (at last follow-up)No. of patients
ITP 362 
 Primary ITP 269 
 Secondary ITP 93 
  Evan's syndrome 14 
  Systemic lupus erythematosus 13 
  Drug-induced ITP 
  Antiphospholipid antibody syndrome 
  Helicobacter pylori 
  Hepatitis C 
  ITP in pregnancy 
  Common variable immune deficiency 
  HIV 
  ITP following nonspecific viral illness or infection 
  Chronic lymphocytic leukemia 
  Lymphoproliferative disease 
  Other associated autoimmune conditions 15 
Nonimmune thrombocytopenia 149 
 Familial thrombocytopenia (suspected or confirmed) 35 
 Splenomegaly 27 
 Incidental thrombocytopenia of pregnancy 20 
 Myelodysplastic syndrome 20 
 Liver disease 16 
 Pseudothrombocytopenia 13 
 Alcohol-related thrombocytopenia 
 Pancytopenia 
 Thrombocytopenia associated with malignancy 
 Other 
Isolated mild thrombocytopenia (100-150 × 109/L) 67 
Other immune platelet disorders 23 
 Thrombotic microangiopathy 19 
 Cyclic thrombocytopenia 
Unknown 13 
Total 614 

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