Table 2.

HRQoL outcomes by depression group

HRQoL domainAll patients (N = 141)SCD with depression*SCD without depressionP
Physical functioning 64.7 ± 25.2 50.1 ± 23.0 72.4 ± 22.7 <.001 
Role physical 58.6 ± 28.5 43.5 ± 30.0 66.6 ± 24.2 <.001 
Role emotional 69.9 ± 28.8 53.2 ± 29.6 78.9 ± 24.1 <.001 
Vitality 50.7 ± 23.6 34.7 ± 22.8 59.4 ± 19.3 <.001 
Mental health 70.5 ± 19.2 56.2 ± 19.5 78.1 ± 14.0 <.001 
Social functioning 59.9 ± 28.2 43.9 ± 24.1 68.5 ± 26.6 <.001 
Bodily pain 55.8 ± 26.6 41.5 ± 21.7 63.5 ± 25.9 <.001 
General health 43.8 ± 24.5 31.3 ± 21.5 51.0 ± 23.0 <.001 
HRQoL domainAll patients (N = 141)SCD with depression*SCD without depressionP
Physical functioning 64.7 ± 25.2 50.1 ± 23.0 72.4 ± 22.7 <.001 
Role physical 58.6 ± 28.5 43.5 ± 30.0 66.6 ± 24.2 <.001 
Role emotional 69.9 ± 28.8 53.2 ± 29.6 78.9 ± 24.1 <.001 
Vitality 50.7 ± 23.6 34.7 ± 22.8 59.4 ± 19.3 <.001 
Mental health 70.5 ± 19.2 56.2 ± 19.5 78.1 ± 14.0 <.001 
Social functioning 59.9 ± 28.2 43.9 ± 24.1 68.5 ± 26.6 <.001 
Bodily pain 55.8 ± 26.6 41.5 ± 21.7 63.5 ± 25.9 <.001 
General health 43.8 ± 24.5 31.3 ± 21.5 51.0 ± 23.0 <.001 
*

Defined as a reported BDI score of >14 or a BDI score of <14 while actively receiving therapy for depression.

Defined as BDI score ≤14.

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