Characteristics of patients with and without depression
| Characteristics . | SCD with depression* (n = 50) . | SCD without depression† (n = 92) . | P . |
|---|---|---|---|
| Female, n (%) | 36 (72.0) | 45 (48.9) | <.01 |
| Age, y, mean (SD) | 35.4 (11.8) | 33.7 (13.4) | .44 |
| Age group, y, n (%) | .98 | ||
| 18-34 | 28 (56.0) | 51 (55.4) | — |
| 35-49 | 15 (30.0) | 29 (31.5) | — |
| ≥50 | 7 (14.0) | 12 (13.0) | — |
| BMI, kg/m2, mean (SD) | 42.4 (72.7) | 31.9 (40.0) | .27 |
| SCD diagnosis, n (%) | .18 | ||
| SS | 28 (56.0) | 63 (68.5) | — |
| Sβ0 thalassemia | 1 (2.0) | 5 (5.4) | — |
| SC | 15 (30.0) | 20 (21.7) | — |
| Sβ+ thalassemia | 5 (10.0) | 4 (4.4) | — |
| SOArab | 1 (2.0) | 0 (0.0) | — |
| Severity score, n (%) | .93 | ||
| 0 | 11 (22) | 23 (25) | — |
| 1 | 18 (36) | 36 (39) | — |
| 2 | 11 (22) | 20 (22) | — |
| 3 | 7 (14) | 9 (10) | — |
| 4 | 3 (6) | 4 (4) | — |
| Insurance, n (%) | .75 | ||
| Medicaid | 19 (44.2) | 41 (52.6) | — |
| Medicare | 10 (23.3) | 14 (18.0) | — |
| Private | 7 (16.3) | 13 (16.7) | — |
| No insurance/self-pay | 2 (4.7) | 5 (6.4) | — |
| Other | 5 (11.6) | 5 (6.4) | — |
| Characteristics . | SCD with depression* (n = 50) . | SCD without depression† (n = 92) . | P . |
|---|---|---|---|
| Female, n (%) | 36 (72.0) | 45 (48.9) | <.01 |
| Age, y, mean (SD) | 35.4 (11.8) | 33.7 (13.4) | .44 |
| Age group, y, n (%) | .98 | ||
| 18-34 | 28 (56.0) | 51 (55.4) | — |
| 35-49 | 15 (30.0) | 29 (31.5) | — |
| ≥50 | 7 (14.0) | 12 (13.0) | — |
| BMI, kg/m2, mean (SD) | 42.4 (72.7) | 31.9 (40.0) | .27 |
| SCD diagnosis, n (%) | .18 | ||
| SS | 28 (56.0) | 63 (68.5) | — |
| Sβ0 thalassemia | 1 (2.0) | 5 (5.4) | — |
| SC | 15 (30.0) | 20 (21.7) | — |
| Sβ+ thalassemia | 5 (10.0) | 4 (4.4) | — |
| SOArab | 1 (2.0) | 0 (0.0) | — |
| Severity score, n (%) | .93 | ||
| 0 | 11 (22) | 23 (25) | — |
| 1 | 18 (36) | 36 (39) | — |
| 2 | 11 (22) | 20 (22) | — |
| 3 | 7 (14) | 9 (10) | — |
| 4 | 3 (6) | 4 (4) | — |
| Insurance, n (%) | .75 | ||
| Medicaid | 19 (44.2) | 41 (52.6) | — |
| Medicare | 10 (23.3) | 14 (18.0) | — |
| Private | 7 (16.3) | 13 (16.7) | — |
| No insurance/self-pay | 2 (4.7) | 5 (6.4) | — |
| Other | 5 (11.6) | 5 (6.4) | — |
Sβ0 thalassemia, double heterozygous for hemoglobin S and β0 thalassemia; Sβ+ thalassemia, double heterozygous for hemoglobin S and β+ thalassemia; SC, double heterozygous for hemoglobin S and hemoglobin C; SOArab, double heterozygous for hemoglobin S and hemoglobin O Arab; SS, homozygous sickle cell disease.
Defined as a reported BDI score of >14 or a BDI score of <14 while actively receiving therapy for depression.
Defined as a BDI score ≤14.